6 results on '"Ryosuke Yokoi"'
Search Results
2. Concise and stereoselective synthesis of 2,5- and 2,4-disubstituted thiazole amino acid subunits for synthesizing thiazole-containing peptides
- Author
-
Sayuri Akasako, Ryota Nakayama, Junya Hakoda, Rina Takahashi, Naoyoshi Maezaki, Takuji Magata, Ryosuke Yokoi, Yoshimi Hirokawa, Ryota Miyazaki, Shotaro Nojiri, Munetaka Nishida, Aya Tanaka, and Yusuke Moriguchi
- Subjects
chemistry.chemical_classification ,010405 organic chemistry ,Stereochemistry ,Organic Chemistry ,Imine ,chemistry.chemical_element ,Biological activity ,010402 general chemistry ,01 natural sciences ,Biochemistry ,0104 chemical sciences ,Amino acid ,chemistry.chemical_compound ,chemistry ,Drug Discovery ,Lithium ,Stereoselectivity ,Thiazole - Abstract
A concise, highly stereoselective synthesis of 2,4- and 2,5-disubstituted thiazole amino acids was developed. These are important building blocks for various biologically active thiazole-containing natural peptides and their regioisomeric analogues. The fundamental reactions are diastereoselective addition of (4- or 5-bromothiazol-2-yl)lithium to N-tert-butanesulfinyl imine with subsequent Pd-catalyzed phenoxycarbonylation.
- Published
- 2019
3. Significance of country-specific context in metal scarcity assessment from a perspective of short-term mining capacity
- Author
-
Keisuke Nansai, Hiroki Hatayama, Masaharu Motoshita, and Ryosuke Yokoi
- Subjects
Economics and Econometrics ,Natural resource economics ,media_common.quotation_subject ,0211 other engineering and technologies ,Context (language use) ,02 engineering and technology ,010501 environmental sciences ,01 natural sciences ,Term (time) ,Scarcity ,Sustainability ,Threatened species ,Production (economics) ,021108 energy ,Business ,Waste Management and Disposal ,0105 earth and related environmental sciences ,media_common - Abstract
The sustainability of metal use is threatened by increasing global demand. The concept of scarcity in mining capacity is of particular relevance to the sustainability of metals; it represents an imbalance between availability and mine production and is determined by socio-economic conditions. Although socio-economic conditions vary by region or country, few studies have assessed the scarcity in mining capacity of metals on such regional scales, which fails to assess potential risks for local sustainability. Here, we propose a country-specific indicator for the assessment of scarcity in mining capacity of metals that reflects differences in national conditions. We apply our methodology to 16 representative metals for 2000, 2010 and 2017. The results demonstrate our indicator of country-specific scarcity varies by 1-3 orders of magnitude for the metals considered, depending on reserves and mine production in producing countries. Furthermore, an indicator that represents the degree of concentrated production in high-scarcity countries is introduced, which reveals the dependency on high-scarcity countries for Al, REE, Li, and Sn. For the assessment of the effects of specific demand on the potential risks of threatening local sustainability, we define the severity of mine production that represents the magnitude of the potential risks determined by both country-specific mine production and scarcity. Analysis of metal scarcity considering country-specific conditions can reveal the potential risks for local sustainability associated with metal production and support metal users to seek effective solutions to reduce the potential risks, which is not considered in existing criticality assessments.
- Published
- 2021
4. International inequality in in-use metal stocks: What it portends for the future
- Author
-
Ryosuke Yokoi and Takuma Watari
- Subjects
Economics and Econometrics ,education.field_of_study ,Sociology and Political Science ,Inequality ,Natural resource economics ,020209 energy ,media_common.quotation_subject ,Population ,Developing country ,02 engineering and technology ,010501 environmental sciences ,Management, Monitoring, Policy and Law ,International inequality ,01 natural sciences ,Contraction and Convergence ,0202 electrical engineering, electronic engineering, information engineering ,Economics ,Per capita ,Carrying capacity ,education ,Law ,Stock (geology) ,0105 earth and related environmental sciences ,media_common - Abstract
In-use stocks of metals underpin essential services in the world's economy and drive long-term anthropogenic metal cycles. Given this fact, the global distribution patterns of metal stocks provide a fundamental basis for examining ways to satisfy the basic needs of an expanding global population within the Earth's carrying capacity. Here we show that the in-use stocks of six major metals (steel, aluminum, copper, zinc, lead and nickel) are distributed very unevenly across 231 countries and regions. According to our analysis, the highest 20% of the world's population (ordered in terms of metal stock per capita) accounts for approximately 60-75% of the world's total metal stock, while the lowest 20% accounts for only about 1%. International inequality in metal stocks has been decreasing over time due to the strong growth in developing countries, mainly those in Asia. However, our analysis shows that the continued reduction of metal stock inequality through this growth-led pathway will put heavy pressure on the environment, with a 2-3-fold increase in global metal demand by mid-21st century. These findings imply the need for alternative stock evolution patterns involving contraction and convergence, where global per capita metal stock growth stabilizes at a level below that current for developed countries.
- Published
- 2021
5. An Extended Model for Tracking Accumulation Pathways of Materials Using Input–Output Tables: Application to Copper Flows in Japan
- Author
-
Ryosuke Yokoi, Yuichi Moriguchi, and Jun Nakatani
- Subjects
020209 energy ,Geography, Planning and Development ,chemistry.chemical_element ,TJ807-830 ,02 engineering and technology ,010501 environmental sciences ,Management, Monitoring, Policy and Law ,TD194-195 ,01 natural sciences ,Renewable energy sources ,endogenous sector ,Extended model ,0202 electrical engineering, electronic engineering, information engineering ,GE1-350 ,input–output table ,Process engineering ,Stock (geology) ,0105 earth and related environmental sciences ,processing form ,Environmental effects of industries and plants ,Renewable Energy, Sustainability and the Environment ,business.industry ,Material flow analysis ,Copper ,Environmental sciences ,material flow analysis ,chemistry ,accompaniment ,copper ,Final demand ,Environmental science ,Resource use ,business ,accumulation - Abstract
Recycling has become increasingly important as a means to mitigate not only waste issues but also problems related to primary resource use, such as a decrease in resource availability. In order to promote and plan future recycling efficiently, detailed information on the material stock in society is important. For a detailed analysis of material stocks, quantitative information on flows of a material, such as its accumulation pathways, final destinations, and its processing forms, are required. This paper develops a model for tracking accumulation pathways of materials using input–output tables (IOTs). The main characteristics of the proposed model are as follows: (1) accumulations in sectors other than the final demand sectors (i.e., endogenous sectors) are explicitly evaluated, (2) accumulations as accompaniments to products, such as containers and packaging, are distinguished from the products, and (3) processing forms of materials are considered. The developed model is applied to analyze copper flows in Japan using the Japanese IOTs for the year 2011. The results show that accumulations of copper in endogenous sectors were not negligibly small (9.24% of the overall flow). Although accumulations of copper as accompaniments were very small, they may be larger for other materials that are largely used as containers or packaging. It was found that the destinations of copper showed different characteristics depending on the processing forms.
- Published
- 2018
- Full Text
- View/download PDF
6. Calculation of Characterization Factors of Mineral Resources Considering Future Primary Resource Use Changes: A Comparison between Iron and Copper
- Author
-
Yuichi Moriguchi, Jun Nakatani, and Ryosuke Yokoi
- Subjects
Resource (biology) ,Life cycle impact assessment ,Secondary resource ,020209 energy ,lcsh:TJ807-830 ,Geography, Planning and Development ,lcsh:Renewable energy sources ,02 engineering and technology ,010501 environmental sciences ,Management, Monitoring, Policy and Law ,future demand ,01 natural sciences ,0202 electrical engineering, electronic engineering, information engineering ,life cycle impact assessment ,shared socioeconomic pathways ,lcsh:Environmental sciences ,0105 earth and related environmental sciences ,lcsh:GE1-350 ,material flow analysis ,characterization factor ,surplus cost ,secondary resource ,Renewable Energy, Sustainability and the Environment ,lcsh:Environmental effects of industries and plants ,Material flow analysis ,Environmental economics ,Mineral resource classification ,lcsh:TD194-195 ,Environmental science ,Resource use - Abstract
The future availability of mineral resources has attracted much attention; therefore, a quantitative evaluation of the potential impacts of resource use on future availability is important. Although the surplus cost model is often recommended among the existing endpoint characterization models of mineral resources, it has a shortcoming as it does not consider the changes in future primary resource use. This paper introduces a new characterization model considering future primary resource use changes, due to future changes in total demand and secondary resource use. Using material flow analysis, this study estimated time-series primary resource use for iron and copper for five shared socioeconomic pathways (SSPs) and a constant total demand scenario. New characterization factors, i.e., demand change-based surplus costs (DCSC), are calculated for each resource. In all of the SSPs, the calculated DCSCs are larger than the conventional surplus costs (SC) for both iron and copper. The DCSC, relative to the SC of copper, is larger than that of iron for all of the SSPs, which suggests that the potential impacts of copper use, relative to iron, will be underestimated, unless future primary resource use changes are considered. In calculating DCSC for other resources, it is important to choose an appropriate approach for forecasting future total demands.
- Published
- 2018
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.