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Start Over Author "Xingyu Qiang" Topic 01 natural sciences
2 results on '"Xingyu Qiang"'

1. Data-Driven Method for Flow Sensing of Aerodynamic Parameters Using Distributed Pressure Measurements

Author

Xin Wen, Kaiwen Zhou, Xingyu Qiang, Simeng Zhao, Luanliang Zhou, and Yingzheng Liu

Subjects
020301 aerospace & aeronautics, Angle of attack, Flow (psychology), Aerospace Engineering, 02 engineering and technology, Inflow, Aerodynamics, Mechanics, 01 natural sciences, Pressure sensor, 010305 fluids & plasmas, law.invention, Flow separation, Pressure measurement, 0203 mechanical engineering, Particle image velocimetry, law, 0103 physical sciences, Environmental science
Abstract

The real-time identification of inflow aerodynamic parameters such as the flow separation situation, angle of attack, and inflow velocity is challenging. In this paper, a new data-driven strategy i...

Published
2021
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2. A mitochondria-specific fluorescent probe based on triazolopyridine formation for visualizing endogenous hypochlorous acid in living cells and zebrafish

Author

Xiu Mengxue, Xingyu Qiang, Yuan Guo, Donghuan Sun, Hao Teng, Yanhui Zhang, Haoyang Tang, and Jingye Tian

Subjects
Hypochlorous acid, Endogeny, 02 engineering and technology, Mitochondrion, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, chemistry.chemical_compound, In vivo, Materials Chemistry, medicine, Electrical and Electronic Engineering, Instrumentation, Zebrafish, chemistry.chemical_classification, Reactive oxygen species, biology, Metals and Alloys, 021001 nanoscience & nanotechnology, Condensed Matter Physics, biology.organism_classification, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry, Biophysics, Triazolopyridine, 0210 nano-technology, Oxidative stress
Abstract

Biological hypochlorous acid (HOCl), a reactive oxygen species (ROS) with high activity, plays a crucial role in normal biochemical functions and abnormal pathological processes related to oxidative stress. However, “eco-friendly” tools to unambiguously monitor subtle changes of mitochondrial HOCl in vivo are limited. Herein, a novel mitochondria-specific and “eco-friendly” fluorescent probe (NM1) using triphenylphosphonium as the targeting group is designed for the detection of biological HOCl by a HOCl-promoted triazolopyridine formation strategy. This HOCl-promoted triazolopyridine formation reaction is fast and does not release additional substances except H2O. Therefore, NM1 is not only an “eco-friendly” HOCl probe, but also can target mitochondria to monitor biological HOCl in situ and in real time. Better still, our probe NM1 is capable to image endogenous HOCl in living HepG2 cells and zebrafish.

Published
2020
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