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Your search keyword '"Thomas Chaigne"' showing total 7 results
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7 results on '"Thomas Chaigne"'

1. Photoacoustic imaging beyond the acoustic diffraction-limit with dynamic speckle illumination and sparse joint support recovery

Author

Sylvain Gigan, Eliel Hojman, Emmanuel Bossy, Thomas Chaigne, Oren Solomon, Ori Katz, Yonina C. Eldar, Department of Applied Physics, Hebrew University of Jerusalem, Laboratoire Kastler Brossel (LKB (Jussieu)), Université Pierre et Marie Curie - Paris 6 (UPMC)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Department of Computer Science [Haifa], University of Haifa [Haifa], Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères] (LIPhy), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
0301 basic medicine, FOS: Computer and information sciences, Computer science, Computer Science - Information Theory, Photoacoustic imaging in biomedicine, FOS: Physical sciences, Image processing, 01 natural sciences, 010309 optics, 03 medical and health sciences, Speckle pattern, Optics, Optical imaging, Signal-to-noise ratio, 0103 physical sciences, Image resolution, ComputingMilieux_MISCELLANEOUS, Dynamic speckle, [PHYS]Physics [physics], business.industry, Information Theory (cs.IT), Atomic and Molecular Physics, and Optics, Wavelength, 030104 developmental biology, Compressed sensing, business, Optics (physics.optics), Physics - Optics
Abstract

In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. Recently, it was demonstrated that it is possible to surpass the acoustic diffraction limit by analyzing fluctuations in a set of photoacoustic images obtained under unknown speckle illumination patterns. Here, we purpose an approach to boost reconstruction fidelity and resolution, while reducing the number of acquired images by utilizing a compressed sensing computational reconstruction framework. The approach takes into account prior knowledge of the system response and sparsity of the target structure. We provide proof of principle experiments of the approach and demonstrate that improved performance is obtained when both speckle fluctuations and object priors are used. We numerically study the expected performance as a function of the measurement's signal to noise ratio and sample spatial-sparsity. The presented reconstruction framework can be applied to analyze existing photoacoustic experimental data sets containing dynamic fluctuations.

Published
2017
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2. Super-resolution photoacoustic imaging via flow-induced absorption fluctuations

Author

Sergey Vilov, Bastien Arnal, Emmanuel Bossy, Thomas Chaigne, Ori Katz, Laboratoire Kastler Brossel (LKB (Jussieu)), Université Pierre et Marie Curie - Paris 6 (UPMC)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Charite, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères] (LIPhy), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Department of Applied Physics, Hebrew University of Jerusalem, Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Photoacoustic effect, [PHYS]Physics [physics], Absorption (acoustics), Chemistry, business.industry, Physics::Medical Physics, Physics::Optics, 02 engineering and technology, Acoustic wave, 021001 nanoscience & nanotechnology, 01 natural sciences, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, 010309 optics, Photoacoustic Doppler effect, Wavelength, Optics, Attenuation coefficient, 0103 physical sciences, Microscopy, 0210 nano-technology, business, Image resolution, ComputingMilieux_MISCELLANEOUS
Abstract

In deep-tissue photoacoustic imaging, optical-contrast images of deep-lying structures are formed by recording acoustic waves that are generated by optical absorption. Although photoacoustics is perhaps the leading technique for high-resolution deep-tissue optical imaging, its spatial resolution is fundamentally limited by the acoustic wavelength, which is orders of magnitude longer than the optical diffraction limit. Here, we present an approach for surpassing the acoustic diffraction limit in photoacoustics by exploiting inherent temporal fluctuations in the photoacoustic signals due to sample dynamics, such as those induced by the flow of absorbing red blood cells. This was achieved using a conventional photoacoustic imaging system by adapting concepts from super-resolution fluorescence fluctuation microscopy to the statistical analysis of acoustic signals from flowing acoustic emitters. Specifically, we experimentally demonstrate that flow of absorbing particles and whole human blood yields super-resolved photoacoustic images, and provides static background reduction. By generalizing the statistical analysis to complex-valued signals, we demonstrate super-resolved photoacoustic images that are free from common photoacoustic imaging artifacts caused by band-limited acoustic detection. The presented technique holds potential for contrast-agent-free microvessel imaging, as red blood cells provide a strong endogenous source of naturally fluctuating absorption.

Published
2017
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3. Breaking the acoustic diffraction limit in photoacoustic imaging with multiple speckle illumination

Author

Emmanuel Bossy, Thomas Chaigne, Anne Sentenac, Marc Allain, Sylvain Gigan, Jérôme Gateau, and Ori Katz

Subjects
Diffraction, Physics, business.industry, Attenuation, Resolution (electron density), 02 engineering and technology, 021001 nanoscience & nanotechnology, 01 natural sciences, Signal, 010309 optics, Photoacoustic Doppler effect, Speckle pattern, Optics, 0103 physical sciences, Ultrasonic sensor, Deconvolution, 0210 nano-technology, business
Abstract

In deep photoacoustic imaging, resolution is inherently limited by acoustic diffraction, and ultrasonic frequencies cannot be arbitrarily increased because of attenuation in tissue. Here we report on the use of multiple speckle illumination to perform super resolution photoacoustic imaging. We show that the analysis of speckle-induced second-order fluctuations of the photoacoustic signal combined with deconvolution enables to resolve optically absorbing structures below the acoustic diffraction limit.

Published
2016
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4. Improving photoacoustic-guided optical focusing in scattering media by spectrally filtered detection

Author

Claude Boccara, Emmanuel Bossy, Thomas Chaigne, Sylvain Gigan, Jérôme Gateau, Ori Katz, Institut Langevin - Ondes et Images (UMR7587) (IL), Sorbonne Université (SU)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Paris (UP)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Kastler Brossel (LKB (Lhomond)), Université Pierre et Marie Curie - Paris 6 (UPMC)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, Light, Optical Phenomena, Frequency band, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, Photoacoustic imaging in biomedicine, FOS: Physical sciences, 02 engineering and technology, Low frequency, 01 natural sciences, Signal, Feedback, 010309 optics, Photoacoustic Techniques, Optics, 0103 physical sciences, Broadband, Scattering, Radiation, business.industry, Scattering, Signal Processing, Computer-Assisted, 021001 nanoscience & nanotechnology, Atomic and Molecular Physics, and Optics, Transducer, [SPI.OPTI]Engineering Sciences [physics]/Optics / Photonic, 0210 nano-technology, business, Optics (physics.optics), Physics - Optics
Abstract

International audience; We study the potential of photoacoustic guidance for light focusing through scattering samples via wavefront-shaping and iterative optimization. We experimentally demonstrate that the focusing efficiency on an extended absorber can be improved by iterative optimization of the high frequency components of the broadband photoacous-tic signal detected with a spherically focused transducer. We demonstrate more than 12-fold increase in the photoacoustic signal generated by a 30 μm wire using a narrow frequency band around 60 MHz. By monitoring the speckle pattern evolution during the optimization process with a CCD camera, we experimentally confirm that such optimization leads to a smaller optical focus than what would be obtained by optimizing lower frequencies of the photoacoustic feedback.

Published
2014
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5. Light Focusing and Two-Dimensional Imaging Through Scattering Media using the Photoacoustic Transmission-Matrix with an Ultrasound Array

Author

Jérôme Gateau, Sylvain Gigan, Ori Katz, Emmanuel Bossy, Thomas Chaigne, Institut Langevin - Ondes et Images (UMR7587) (IL), Sorbonne Université (SU)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Paris (UP)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, Light, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, Photoacoustic imaging in biomedicine, FOS: Physical sciences, Transmission matrix, 02 engineering and technology, 01 natural sciences, Signal, 010309 optics, Two dimensional imaging, Photoacoustic Techniques, Optics, Nephelometry and Turbidimetry, 0103 physical sciences, Scattering, Radiation, Lighting, business.industry, Scattering, Lasers, Ultrasound, OCIS codes: (110.5120) Photoacoustic imaging, (140.3300) Laser beam shaping, (110.0113) Imaging through turbidmedia, (110.1080) Active or adaptive optics, Equipment Design, 021001 nanoscience & nanotechnology, Image Enhancement, Microarray Analysis, Atomic and Molecular Physics, and Optics, Equipment Failure Analysis, Plant Leaves, [SPI.OPTI]Engineering Sciences [physics]/Optics / Photonic, Elasticity Imaging Techniques, 0210 nano-technology, business, Physics - Optics, Optics (physics.optics)
Abstract

International audience; We implement the photoacoustic transmission matrix approach on a two-dimensional photoacoustic imaging system, using a 15 MHz linear ultrasound array. Using a black leaf skeleton as a complex absorbing structure, we demonstrate that the photoacoustic transmission matrix approach allows to reveal structural features that are invisible in conventional photoacoustic images, as well as to selectively control light focusing on absorbing targets, leading to a local enhancement of the photoacoustic signal.

Published
2014
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6. Controlling light in scattering media non-invasively using the photoacoustic transmission matrix

Author

Emmanuel Bossy, Thomas Chaigne, Mathias Fink, Ori Katz, Sylvain Gigan, Albert C. Boccara, Institut Langevin - Ondes et Images (UMR7587) (IL), Sorbonne Université (SU)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Paris (UP)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, Optical contrast, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, Photoacoustic imaging in biomedicine, FOS: Physical sciences, Transmission matrix, 02 engineering and technology, Light delivery, 01 natural sciences, 010309 optics, Optics, Optical imaging, 0103 physical sciences, Adaptive optics, [SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph], [PHYS]Physics [physics], [PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics], business.industry, Scattering, 021001 nanoscience & nanotechnology, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, [SPI.OPTI]Engineering Sciences [physics]/Optics / Photonic, 0210 nano-technology, business, Physics - Optics, Optics (physics.optics)
Abstract

International audience; Optical wavefront shaping has emerged as a powerful tool for manipulating light in strongly scattering media. It enables diffraction-limited focusing and imaging at depths where conventional microscopy techniques fail. However, to date, most examples of wavefront shaping have relied on direct access to the targets or implanted probes, and the challenge is to apply it non-invasively inside complex samples. Recently, ultrasonic-tagging techniques have been utilized successfully, but these allow only small acoustically tagged volumes to be addressed at each measurement. Here, we introduce an approach that allows the non-invasive measurement of an optical transmission matrix over a large volume, inside complex samples, using a standard photoacoustic imaging set-up. We demonstrate the use of this matrix for detecting, localizing and selectively focusing light on absorbing targets through diffusive samples, as well as for extracting the scattering medium properties. Combining the transmission-matrix approach with the advantages of photoacoustic imaging opens a path towards deep-tissue imaging and light delivery utilizing endogenous optical contrast.

Published
2013
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7. Improving visibility in photoacoustic imaging using dynamic speckle illumination

Author

Jérôme Gateau, Ori Katz, Thomas Chaigne, Emmanuel Bossy, Sylvain Gigan, Institut Langevin - Ondes et Images (UMR7587) (IL), Sorbonne Université (SU)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Paris (UP)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Materials science, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, FOS: Physical sciences, Photoacoustic imaging in biomedicine, 02 engineering and technology, 01 natural sciences, Absorption, Photoacoustic Techniques, 010309 optics, Speckle pattern, Optics, 0103 physical sciences, Dynamic speckle, Pixel, Phantoms, Imaging, business.industry, Optical Imaging, 021001 nanoscience & nanotechnology, Atomic and Molecular Physics, and Optics, Homogeneous, [SPI.OPTI]Engineering Sciences [physics]/Optics / Photonic, 0210 nano-technology, business, Large size, Physics - Optics, Optics (physics.optics)
Abstract

In high-frequency photoacoustic imaging with uniform illumination, homogeneous photo-absorbing structures may be invisible because of their large size or limited-view issues. Here we show that, by exploiting dynamic speckle illumination, it is possible to reveal features which are normally invisible with a photoacoustic system comprised of a 20MHz linear ultrasound array. We demonstrate imaging of a 5 mm diameter absorbing cylinder and a 30 micrometer black thread arranged in a complex shape. The hidden structures are directly retrieved from photoacoustic images recorded for different random speckle illuminations of the phantoms by assessing the variation in the value of each pixel over the illumination patterns., Comment: 4 pages, 3 figures, Accepted in Optics letters

Published
2013
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