1. Self-Assembled Multivalent Ag-SR Coordination Polymers with Phosphatase-Like Activity
- Author
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Mei-Xia Yao, Rui-Xue Ji, Ying-Juan Cao, Leonard J. Prins, Ning Liu, Jiang-Shan Shen, Xiangying Sun, and Yun-Bao Jiang
- Subjects
Coordination polymer ,Metal ions in aqueous solution ,Supramolecular chemistry ,010402 general chemistry ,01 natural sciences ,Catalysis ,supramolecular chemistry ,Metal ,Ag-SR coordination polymers ,Artificial phosphatases ,homogeneous catalysis ,self-assembly ,chemistry.chemical_compound ,Polymer chemistry ,Reactivity (chemistry) ,Alkyl ,chemistry.chemical_classification ,010405 organic chemistry ,Organic Chemistry ,General Chemistry ,Polymer ,0104 chemical sciences ,chemistry ,visual_art ,visual_art.visual_art_medium ,Self-assembly - Abstract
We show herein the phosphatase-like catalytic activity of coordination polymers obtained after adding Ag + -ions to thiols bearing hydrophobic alkyl chains terminated with a 1,4,7-triazacyclononane (TACN) group. The subsequent addition of Zn 2+ -ions to the self-assembled polymers resulted in the formation of multivalent metal coordination polymers capable of catalysing the transphosphorylation of an RNA-model compound (2-hydroxypropyl-4-nitrophenyl phosphate, HPNPP) with high reactivity. Analysis of a series of metal ions showed that the highest catalytic activity was obtained when Ag + -ions were used as the first metal ions to construct the backbone of the coordination polymer through interaction with the -SH group followed by Zn 2+ -ions as the second metal ions complexed by the TACN-macrocycle. Furthermore, it was demonstrated that the catalytic activity could be modulated by changing the length of the hydrophobic alkyl chain.
- Published
- 2021