1. Standpoint on the priority of TNTs and CNTs as targeted drug delivery systems
- Author
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Géza Regdon, Tamás Sovány, Klára Pintye-Hódi, and Yasmin Ranjous
- Subjects
0301 basic medicine ,Pharmacology ,Nanotubes ,Materials science ,Biocompatibility ,Nanotubes, Carbon ,Nanoparticle ,Biocompatible Materials ,Nanotechnology ,Carbon nanotube ,law.invention ,Titanate nanotubes ,03 medical and health sciences ,Drug Delivery Systems ,030104 developmental biology ,0302 clinical medicine ,Targeted drug delivery ,law ,030220 oncology & carcinogenesis ,Drug Discovery ,Drug delivery ,Humans ,Nanoparticles ,Surface modification - Abstract
Conventional drug delivery systems have limitations according to their toxicity and poor solubility, bioavailability, stability, and pharmacokinetics (PK). Here, we highlight the importance of functionalized titanate nanotubes (TNTs) as targeted drug delivery systems. We discuss the differences in the physicochemical properties of TNTs and carbon nanotubes (CNTs) and focus on the use of functionalization to improve their characteristics. TNTs are promising materials for drug delivery systems because of their superb properties compared with CNTs, such as their processability, wettability, and biocompatibility. Functionalization improves nanoparticles (NPs) via their surface modification and enables them to achieve the targeted therapy. more...
- Published
- 2019
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