1. Correction: Prevalence and risk factors of chlamydia infection in Hong Kong: A population-based geospatial household survey and testing
- Author
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Ngai Sze Wong, Heidi Yin Hai Miu, Francois Yeung Fong, Joseph D. Tucker, William Wong, King Man Ho, Yanping Zhao, William L. Parish, Li Gang Yang, and Michael Emch
- Subjects
Male ,Physiology ,Population Dynamics ,lcsh:Medicine ,Artificial Gene Amplification and Extension ,Urine ,computer.software_genre ,Pathology and Laboratory Medicine ,Polymerase Chain Reaction ,Geographical locations ,Chlamydia Infection ,Household survey ,0302 clinical medicine ,Risk Factors ,Prevalence ,Medicine and Health Sciences ,Mass Screening ,030212 general & internal medicine ,Chlamydia ,lcsh:Science ,Multidisciplinary ,030503 health policy & services ,Age Factors ,Middle Aged ,Bacterial Pathogens ,Body Fluids ,Geography ,Infectious Diseases ,Chlamydia Trachomatis ,Medical Microbiology ,Research Design ,Hong Kong ,Female ,Pathogens ,Anatomy ,0305 other medical science ,Research Article ,Adult ,Census ,Geospatial analysis ,Asia ,Adolescent ,Sexually Transmitted Diseases ,Population based ,Research and Analysis Methods ,Microbiology ,Young Adult ,03 medical and health sciences ,Sex Factors ,Environmental health ,medicine ,Humans ,Molecular Biology Techniques ,Microbial Pathogens ,Molecular Biology ,Survey Research ,Bacteria ,Population Biology ,lcsh:R ,Organisms ,Correction ,Biology and Life Sciences ,Chlamydia Infections ,medicine.disease ,Health Surveys ,Geographic Distribution ,lcsh:Q ,People and places ,computer - Abstract
Background Chlamydia causes infertility and increases risk of HIV infection, and population-based studies provide essential information for effective infection control and prevention. This study examined Chlamydia trachomatis prevalence and risk factors among a representative sample of 18-49-year-old residents in Hong Kong. Methods Census boundary map of 412 constituency areas was used as primary sampling units to construct the sampling frame and, residential buildings and units were randomly selected using geospatial modelling. A questionnaire on sexual practice and health was conducted, and polymerase chain reaction was used to test the urine for genital chlamydial infection. Invitation letters were sent to the selected households and a team of interviewers were sent to recruit one subject per household. Prevalence data was weighted according to the 2011 census and risk factors identified through logistic regression. Results Among 881 participants (response rate of 24.5%), the overall Chlamydia trachomatis prevalence was low at 1.4% (95%CI 0.8–2.5%) but sexually active young (18–26 years) women had relatively high prevalence (5.8%, 95%CI 1.7–18.2%) in Hong Kong. A unique U-shape disease burden was observed with peaks in younger and older (40–49 years) women. Amongst the sexually active women, the risk factors of Chlamydia trachomatis infection were: younger age (aOR = 25.4, 95% CI 2.81–230); living alone (aOR = 8.99, 95% CI 1.46–55.40); and, among all the sexually active participants, males (including the male partners of the female participants) who had travelled out of Hong Kong in the previous 12 months had higher risks of infection (aOR = 5.35; 95% CI 1.25–22.8). A core-peripheral geographical distribution of Chlamydia trachomatis prevalence was also observed. Conclusion Young and older sexually active women in Hong Kong have high prevalence of chlamydia. Routine screening for sexually active women and young men should be considered. Further research on testing feasibility and linkage-to-care are urgently needed to control the infection.
- Published
- 2018