1. Contrast-enhanced CT longitudinal tail sign as a marker of positive resection margins in adenoid cystic carcinoma of the central airway
- Author
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Le-Kang Yin, Shu-Chao Wang, Yu Zhang, Guangyu Tao, Jin-Wei Qiang, Li-Min Xue, Hong Yu, and Jian-Ding Ye
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Univariate analysis ,Surgical margin ,business.industry ,Adenoid cystic carcinoma ,Odds ratio ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,030220 oncology & carcinogenesis ,medicine ,Central airway ,Original Article ,Histopathology ,Radiology ,Positive Surgical Margin ,030223 otorhinolaryngology ,Airway ,business ,psychological phenomena and processes - Abstract
BACKGROUND: Due to submucosal infiltration’s biological nature along the airway, adenoid cystic carcinoma (ACC) frequently leaves positive surgical margins. This study evaluated the clinicopathologic, and computed tomography (CT) features for predicting surgical margin status in central airway ACC. METHODS: We retrospectively analyzed the files of 71 patients with ACC of the central airway proven by histopathology and surgery who had presented between January 2010 and December 2018. All patients were classified into positive and negative surgical margin groups according to margin status. Univariate analysis and multivariable logistic regression models were then performed to compare demography, histopathology, and CT characteristics between ACC patients with positive and negative margins. RESULTS: After surgical resection, 59 (83.1%) patients had positive margins, and 12 (16.9%) had negative margins. The contrast-enhanced CT (CECT) longitudinal tail sign (LTS) was identified in 55 of 59 (93.2%) patients with positive margins and was the only feature that had a significant association with positive margins (odds ratio 41.250, 95% CI: 7.886–215.767; P
- Published
- 2021