1. Bulbospinal muscular atrophy (Kennedy disease) responsive to immunoglobulins?
- Author
-
Sabine Pollanz-Petrovic, Katharina Poustka, Elisabeth Lindeck-Pozza, and Josef Finsterer
- Subjects
Pathology ,medicine.medical_specialty ,phenotype ,immunoglobulins ,lcsh:Medicine ,Case Report ,Disease ,Case Reports ,030204 cardiovascular system & hematology ,Dysdiadochokinesia ,Fasciculation ,Kennedy disease ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Wasting ,lcsh:R5-920 ,business.industry ,lcsh:R ,Muscle weakness ,General Medicine ,medicine.disease ,Hypotonia ,nervous system diseases ,polyglutamine disease ,Gynecomastia ,030220 oncology & carcinogenesis ,motor neuron disease ,polyneuropathy ,medicine.symptom ,business ,lcsh:Medicine (General) ,Polyneuropathy - Abstract
A 61 year old man with facial diplegia, quadruparesis, tongue atrophy/fasciculations, bulbar speech, muscle weakness/wasting, hypotonia, tremor, dysdiadochokinesia, absent tendon reflexes, fasciculations, and gynecomastia, received immunoglobulins for suspected immune‐neuropathy with limited benefit. After reconsideration, Kennedy disease was diagnosed upon 44 CAG repeats in AR. In conclusion, immunoglobulins exhibit limited benefit on immune‐neuropathy in patients with coexisting KD., A 61 year old man with facial diplegia, quadruparesis, tongue atrophy/fasciculations, bulbar speech, muscle weakness/wasting, hypotonia, tremor, dysdiadochokinesia, absent tendon reflexes, fasciculations, and gynecomastia, received immunoglobulins for suspected immune‐neuropathy with limited benefit. After reconsideration, Kennedy disease was diagnosed upon 44 CAG repeats in AR. Immunoglobulins exhibit limited benefit on immune‐neuropathy in patients with coexisting KD
- Published
- 2020