1. Frontoparietal Connectivity Neurofeedback Training for Promotion of Working Memory: An fNIRS Study in Healthy Male Participants
- Author
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Mingxi Yang, Meiyun Xia, Guijun Dong, Gu Xiaolei, Shuyu Li, Yuanbin Yang, Daifa Wang, Deyu Li, Wenyu Jiang, Ling Wang, Zehua Wang, and Pengfei Xu
- Subjects
medicine.medical_specialty ,General Computer Science ,media_common.quotation_subject ,Audiology ,working memory ,050105 experimental psychology ,03 medical and health sciences ,0302 clinical medicine ,Promotion (rank) ,medicine ,functional near-infrared spectroscopy ,0501 psychology and cognitive sciences ,General Materials Science ,Electrical and Electronic Engineering ,media_common ,medicine.diagnostic_test ,Working memory ,functional connectivity ,05 social sciences ,General Engineering ,Cognition ,neurofeedback ,Training effect ,Cognitive training ,TK1-9971 ,Quantitative Biology - Neurons and Cognition ,FOS: Biological sciences ,Task analysis ,Neurons and Cognition (q-bio.NC) ,Electrical engineering. Electronics. Nuclear engineering ,Neurofeedback ,Psychology ,Functional magnetic resonance imaging ,030217 neurology & neurosurgery - Abstract
Neurofeedback cognitive training is a promising tool used to promote cognitive functions effectively and efficiently. In this study, we investigated a novel functional near-infrared spectroscopy (fNIRS)-based frontoparietal functional connectivity (FC) neurofeedback training paradigm related to working memory, involving healthy adults. Compared with conventional cognitive training studies, we chose the frontoparietal network, a key brain region for cognitive function modulation, as neurofeedback, yielding a strong targeting effect. In the experiment, 10 participants (test group) received three cognitive training sessions of 15 min using fNIRS-based frontoparietal FC as neurofeedback, and another 10 participants served as the control group. Frontoparietal FC was significantly increased in the test group ( $p =0.03$ ), and the cognitive functions (memory and attention) were significantly promoted compared with the control group (accuracy of 3-back test: $p =0.0005$ , reaction time of 3-back test: $p =0.0009$ ). After additional validations on long-term training effect and on different patient populations, the proposed method exhibited considerable potential to be developed as a fast, effective, and widespread training approach for cognitive function enhancement.
- Published
- 2021