1. Bactericidal and cytotoxic properties of green synthesized nanosilver using Rosmarinus officinalis leaves
- Author
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Asma M. Al-Qahtani, Nada M. Merghani, Ramesa Shafi Bhat, Rasha Ramadan, Eiman M. Ibrahim, Maha H. Daghestani, Badryah Al-Ojayan, Sarah A. Al Rashed, and Wadha Bukhari
- Subjects
0301 basic medicine ,biology ,Traditional medicine ,Renewable Energy, Sustainability and the Environment ,Chemistry ,Health, Toxicology and Mutagenesis ,General Chemical Engineering ,green synthesis ,biology.organism_classification ,Industrial and Manufacturing Engineering ,Rosmarinus ,nanosilver ,rosmarinus officinalis ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Fuel Technology ,030220 oncology & carcinogenesis ,Officinalis ,Environmental Chemistry ,Cytotoxic T cell ,QD1-999 - Abstract
Green synthesized nanoparticles from plant extracts are being used in various biomedical applications, particularly because of their bactericidal and cytotoxic activities. In this study, silver nanoparticles (AgNPs) were successfully synthesized from the Rosmarinus officinalis aqueous leaf extract. Different spectroscopic and microscopic analyses such as ultraviolet-visible (UV-vis) spectroscopy, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy, and energy-dispersive X-ray spectroscopy were performed to verify the biosynthesized AgNPs in our sample. The formation of nanosilver particles was preliminarily confirmed by UV-vis spectroscopy at 400 nm. The presence of carboxylic or amide groups was confirmed by FTIR, for the reduction of the silver ion. Transmission electron microscopy confirmed a particle size of 12–22 nm. The prepared AgNPs showed good antibacterial activity against human pathogens and good cytotoxic activity against the human breast cancer cell line (MDA MB 231). The nanoparticles prepared from R. officinalis can be used for various biomedical applications. more...
- Published
- 2020