1. Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain
- Author
-
Bruno Loi, Marc Dewey, Matthias Gutberlet, Sarah Feger, Audrone Vaitiekiene, Iñaki Gutiérrez-Ibarluzea, Gershan Davis, Mariusz Kruk, Michael Woinke, Gudrun Feuchtner, Juhani Knuuti, Mark Hensey, Fabian Plank, Konrad Neumann, Thomas Zelesny, José Rodríguez-Palomares, Pál Maurovich-Horvat, Nina Rieckmann, Tomasz Harań, Vasco Gama-Ribeiro, Rita Faria, Patrick Donnelly, Marco Francone, Paolo Ibes, Thomas Engstrøm, Adriane Napp, Henryk Dreger, Laura Zajanckauskiene, Iñigo Lecumberri, Antti Saraste, Nada Čemerlić Adjić, Aleksandar N. Neskovic, Erica Thwaite, Jacqueline Müller-Nordhorn, William Hollingworth, Andrejs Erglis, Ignacio Diez, Jonathan D. Dodd, Marina Berzina, Bruno García del Blanco, Stephen Schröder, Filip Adjić, Cezary Kępka, Imre Benedek, Theodora Benedek, Massimo Mancone, Malgorzata Ilnicka Suckiel, Katriona Brooksbank, Radosav Vidakovic, Vojtěch Suchánek, Ioana Rodean, Damien Collison, Daniel Preuß, Mihaela Ratiu, Michael J. Fisher, Béla Merkely, Peter Ball, Luca Saba, Balasz Ruzsics, Klaus F. Kofoed, and Josef Veselka
- Subjects
Male ,Health-related quality of life ,invasive coronary angiography ,Pilot Projects ,sex distribution ,030204 cardiovascular system & hematology ,Chest pain ,Hospital Anxiety and Depression Scale ,Coronary artery disease ,Angina ,0302 clinical medicine ,Quality of life ,Surveys and Questionnaires ,middle aged ,030212 general & internal medicine ,humans ,Computed tomography angiography ,medicine.diagnostic_test ,angina ,chest pain ,computed tomography angiography ,coronary artery disease ,health-related quality of life ,aged ,angina pectoris ,female ,male ,pilot projects ,surveys and questionnaires ,quality of life ,General Medicine ,Middle Aged ,lcsh:R858-859.7 ,Anxiety ,Female ,medicine.symptom ,medicine.medical_specialty ,Atypical Angina ,Angina Pectoris/classification ,lcsh:Computer applications to medicine. Medical informatics ,03 medical and health sciences ,Internal medicine ,medicine ,Humans ,cardiovascular diseases ,Sex Distribution ,Aged ,business.industry ,Research ,Public Health, Environmental and Occupational Health ,Invasive coronary angiography ,A300 ,medicine.disease ,Quality of Life ,Coronary Artery Disease/diagnosis ,business - Abstract
Background: Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary artery disease (CAD) according to angina type, gender, and presence of obstructive CAD.Methods: From the pilot study for the European DISCHARGE trial, we analysed data from 24 sites including 1263 patients (45.9% women, 61.1 ± 11.3 years) who were clinically referred for invasive coronary angiography (ICA; 617 patients) or coronary computed tomography angiography (CTA; 646 patients). Prior to the procedures, patients completed HRQoL questionnaires: the Short Form (SF)-12v2, the EuroQoL (EQ-5D-3 L) and the Hospital Anxiety and Depression Scale.Results: Fifty-five percent of ICA and 35% of CTA patients had typical angina, 23 and 33% had atypical angina, 18 and 28% had non-anginal chest discomfort and 5 and 5% had other chest discomfort, respectively. Patients with typical angina had the poorest physical functioning compared to the other angina groups (SF-12 physical component score; 41.2 ± 8.8, 43.3 ± 9.1, 46.2 ± 9.0, 46.4 ± 11.4, respectively, all age and gender-adjusted p p p Conclusions: Prior to a diagnostic procedure for stable chest pain, HRQoL is associated with chest pain characteristics, but not with obstructive CAD, and is significantly lower in women.Trial registration: Clinicaltrials.gov, NCT02400229.
- Published
- 2020
- Full Text
- View/download PDF