1. Campylobacter fetus bacteremia and meningitis in an acute lymphoblastic leukemia patient undergoing maintenance therapy: a case report
- Author
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Nobuyoshi Mori, Takuya Yamashita, Ryosuke Koyamada, Koki Shimizu, Takahiro Matsuo, Shinichiro Mori, and Ryo Nakatani
- Subjects
Adult ,0301 basic medicine ,medicine.medical_specialty ,Drug-Related Side Effects and Adverse Reactions ,030106 microbiology ,Case Report ,Infectious and parasitic diseases ,RC109-216 ,Campylobacter jejuni ,Gastroenterology ,Meningitis, Bacterial ,Enteritis ,Diagnosis, Differential ,Foodborne Diseases ,03 medical and health sciences ,Campylobacter fetus ,0302 clinical medicine ,Drug Therapy ,Internal medicine ,Campylobacter Infections ,medicine ,Humans ,030212 general & internal medicine ,Neck stiffness ,biology ,business.industry ,Ceftriaxone ,Meropenem ,Precursor Cell Lymphoblastic Leukemia-Lymphoma ,medicine.disease ,biology.organism_classification ,Anti-Bacterial Agents ,Treatment Outcome ,Infectious Diseases ,Campylobacter coli ,Infective endocarditis ,Bacteremia ,Female ,business ,Meningitis - Abstract
Background Campylobacter fetus is an uncommon Campylobacter species, and its infections mainly cause infective endocarditis, aortic aneurysm, and meningitis rather than enteritis. It is more likely to be detected in blood than Campylobacter jejuni or Campylobacter coli, specifically reported in 53% of patients. In our case, C. fetus was detected in both blood and cerebrospinal fluid (CSF) cultures. Case presentation A 33-year-old woman, who was on maintenance chemotherapy for acute lymphoblastic leukemia (ALL), presented to our clinic with chief complaints of severe headache and nausea. Blood and CSF cultures revealed C. fetus. We administrated meropenem 2 g intravenously (IV) every 8 h for 3 weeks, and she was discharged without neurological sequelae. Conclusion We encountered a case of C. fetus meningitis without gastrointestinal symptoms, neck stiffness or jolt accentuation in a patient with ALL. Undercooked beef was considered the source of C. fetus infection in this case, suggesting that the need for a neutropenic diet and safe food handling be considered.
- Published
- 2021
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