1. Clinical Associations of Early Dysnatremias in Critically Ill Neonates and Infants Undergoing Cardiac Surgery
- Author
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Suhong Tong, Jon Kaufman, Christopher M. Ruzas, Daniel Phadke, Suzanne Osorio, Sarah Newman, Jennifer Eshelman, and Eduardo da Cruz
- Subjects
Male ,medicine.medical_specialty ,Colorado ,Heart Diseases ,Critical Illness ,Population ,030204 cardiovascular system & hematology ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Postoperative Complications ,Risk Factors ,Medicine ,Humans ,Prospective Studies ,Cardiac Surgical Procedures ,education ,Prospective cohort study ,Diuretics ,Retrospective Studies ,education.field_of_study ,Hypernatremia ,business.industry ,Incidence ,Sodium ,Infant, Newborn ,Infant ,030208 emergency & critical care medicine ,Retrospective cohort study ,Vascular surgery ,Length of Stay ,medicine.disease ,Respiration, Artificial ,Cardiac surgery ,Intensive Care Units ,Anesthesia ,Pediatrics, Perinatology and Child Health ,Coronary care unit ,Female ,Cardiology and Cardiovascular Medicine ,business ,Hyponatremia - Abstract
Dysnatremias (DN) are common electrolyte disturbances in cardiac critical illness and are known risk factors for adverse outcomes in certain populations. Little information exists on DN in children with cardiac disease admitted to the cardiac intensive care unit (CICU) after undergoing cardiac surgery, either corrective or palliative. The aim was to determine the incidence and adverse outcomes associated with DN in neonates and infants undergoing cardiac surgery. Retrospective cohort and single center study performed at Children’s Hospital Colorado from May 2013 to May 2014, in children under 1 year old admitted to the CICU after undergoing surgery for congenital or acquired cardiac disease. 183 subjects were analyzed. Exclusions: subjects that demonstrated DN before surgery. Serum sodium levels were recorded for the first 72 h post-operatively. DN was present in 54% of the subjects (98/183): hypernatremia in 60 (33%), hyponatremia in 38 (21%). Multivariate analysis revealed that mild hypernatremia (146–150 mmol/dl) and moderate hypernatremia (151–155 mmol/dl) were associated with longer hospital length of stay (LOS, p
- Published
- 2016