1. Preconception counseling, predicting risk and outcomes in women with mWHO 3 and 4 heart disease
- Author
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Mark R. Johnson, Matthew Cauldwell, Sarah Ghonim, Philip J. Steer, Anselm Uebing, Michael A. Gatzoulis, and Lorna Swan
- Subjects
Counseling ,Pediatrics ,Cardiac & Cardiovascular Systems ,Pregnancy, High-Risk ,030204 cardiovascular system & hematology ,mWHO4 ,Severity of Illness Index ,Preconception Care ,mWHO3 ,Cohort Studies ,CONTRACEPTION ,0302 clinical medicine ,Pregnancy ,1102 Cardiorespiratory Medicine and Haematology ,POPULATION ,CARDIOLOGY ,COMPLICATIONS ,education.field_of_study ,030219 obstetrics & reproductive medicine ,Preconception ,Prognosis ,Risk prediction ,EUROPEAN-SOCIETY ,Female ,Maternal death ,Cardiology and Cardiovascular Medicine ,Risk assessment ,Life Sciences & Biomedicine ,Cohort study ,Adult ,medicine.medical_specialty ,Heart Diseases ,Pregnancy Complications, Cardiovascular ,Population ,Directive Counseling ,Risk Assessment ,03 medical and health sciences ,medicine ,Humans ,education ,Adverse effect ,Retrospective Studies ,Science & Technology ,business.industry ,Retrospective cohort study ,CARE ,medicine.disease ,United Kingdom ,Cardiovascular System & Hematology ,REGISTRY ,Cardiovascular System & Cardiology ,business - Abstract
Objective All women with CHD, especially those with more severe disease, should be offered preconception counseling (PCC), to discuss the risk of complications and to plan a future pregnancy. Several scoring system have been devised to estimate the risk of adverse events in pregnancies complicated by maternal heart disease (HD) and while comparisons have been made across the whole population, none have focused on the high-risk population. Methods Retrospective cohort study that included women classed as modified WHO (mWHO) 3 and 4 who had a pregnancy from at least 20weeks gestation between 1994 and 2015 managed within our institution. We assessed how well the quoted risk (at PCC) of an adverse event (maternal or fetal) related to the actual rate of occurrence. We calculated NYHA and CARPREG scores for all patients, and the clinician assessment of percentage risk, to predict the occurrence of an adverse outcome. Results We identified 76 mWHO 3 and 4 women who had a total of 102 pregnancies. However, only in 63 pregnancies had the woman attended PCC. Both maternal and fetal adverse events were common. NYHA did not significantly predict any adverse events, whilst a CARPREG score of >3 score predicted heart failure and mWHO4 score predicted maternal death. However, the best prediction of adverse outcomes was a composite quoted risk (percent) given at PCC. Conclusions Women must have access to PCC as those with worse CARPREG and mWHO scores encounter greater adverse events.
- Published
- 2017
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