1. Acute coronary syndrome in octogenarian patients: results from the international registry of acute coronary syndromes in transitional countries (ISACS-TC) registry
- Author
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Manfrini, O., Dorobantu, M., Vasiljevic, Z., Kedev, S., Knezevic, B., Milicic, D., Dilic, M., Trninic, D., Daullxhiu, I., Gustiene, O., Ricci, B., Martelli, I., Cenko, E., Koller, A., Badimon, L., Bugiardini, R., O. Manfrini, M. Dorobantu, Z. Vasiljevic, S. Kedev, B. Knezevic, D. Milicic, M. Dilic, D. Trninic, I. Daullxhiu, O. Gustiene, B. Ricci, I. Martelli, E. Cenko, A. Koller, L. Badimon, and R. Bugiardini
- Subjects
medicine.medical_specialty ,Acute coronary syndrome ,Elderly ,Octogenarian ,Transitional country ,030204 cardiovascular system & hematology ,Chest pain ,03 medical and health sciences ,0302 clinical medicine ,Reperfusion therapy ,Internal medicine ,medicine ,030212 general & internal medicine ,Myocardial infarction ,acute coronary syndrome ,registry ,transitional countries ,Killip class ,business.industry ,ACUTE CORONARY SYNDROMES ,eldery ,Odds ratio ,medicine.disease ,3. Good health ,Eastern european ,Cardiology ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Cohort study - Abstract
We sought to investigate characteristics, treatment, and outcome of octogenarian patients during hospital stay for acute coronary syndrome (ACS) in a transitional country. This is a cohort study of 437 patients ≥ 80 years old, consecutively admitted with a diagnosis of ACS at 14 hospitals in 8 Eastern European countries reporting data to ISACS-TC registry. The primary endpoint was in-hospital mortality. The mean age of the study population was 83.5 years ; 50.1% of the patients were women. Females, less frequently than males, had a history of myocardial infarction, smoking habit, and episodes of typical chest pain. But they were more often admitted with left ventricular dysfunction. The rate of reperfusion treatment (29.5%) was very low in patients with ST-elevation myocardial infarction (STEMI). Also, most of the overall study population had a non-invasive approach (women, 79% vs. men, 70.6% ; P = 0.042). However, when the coronary anatomy was known, there were no differences in the rates of revascularization between genders. There was no difference in the rates of death between male (21%) and female (21.1%) patients. Univariate and multivariate analyses revealed that the independent predictors (P < 0.05) of death in octogenarians were systolic blood pressure
- Published
- 2014