1. Global impact of the COVID‐19 pandemic on cytopathology practice: Results from an international survey of laboratories in 23 countries
- Author
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Pio Zeppa, Gonca Özgün, Eugeniu Cazacu, Franco Fulciniti, Alessandro D’Amuri, Izidor Kern, Philippe Vielh, Reinhard Büttner, Jamal Musayev, Meltem Öznur, Chiara Casadio, Brenda Sweeney, Marianne Engels, Tajana Štoos-Veić, William C. Faquin, Eduardo Alcaraz-Mateos, Birgit Weynand, Esther Diana Rossi, Béatrix Cochand-Priollet, Claudio Bellevicine, Zubair W. Baloch, Betsy Robinson, Paul A. VanderLaan, Fernando Schmitt, Anandi Lobo, Martha B. Pitman, Kennichi Kakudo, Antonio Ieni, Rima Cepurnaite, Sule Canberk, David N. Poller, Arrigo Capitanio, Marie Louise F. van Velthuysen, Dario Bruzzese, Giancarlo Troncone, Francisco Javier Seguí Iváñez, Pamela Michelow, Ivana Kholová, Pasquale Pisapia, Rinus Voorham, Michal Pyzlak, Lukas Bubendorf, Gabriella Fontanini, Umberto Malapelle, Guido Fadda, Pavlina Botsun, Oksana Sulaieva, Sinchita Roy-Chowdhuri, Catarina Eloy, Francisca Maria Peiró Marqués, Antonino Iaccarino, Chinhua Liu, Giovanni Tuccari, Mauro Saieg, Xiaoyin Sara Jiang, Elena Vigliar, Syed Z. Ali, Zahra Maleki, Maria D. Lozano, Massimo Bongiovanni, Patrizia Viola, Paul Hofman, Spasenija Savic Prince, Vigliar, E., Cepurnaite, R., Alcaraz-Mateos, E., Ali, S. Z., Baloch, Z. W., Bellevicine, C., Bongiovanni, M., Botsun, P., Bruzzese, D., Bubendorf, L., Buttner, R., Canberk, S., Capitanio, A., Casadio, C., Cazacu, E., Cochand-Priollet, B., D'Amuri, A., Eloy, C., Engels, M., Fadda, G., Fontanini, G., Fulciniti, F., Hofman, P., Iaccarino, A., Ieni, A., Jiang, X. S., Kakudo, K., Kern, I., Kholova, I., Liu, C., Lobo, A., Lozano, M. D., Malapelle, U., Maleki, Z., Michelow, P., Musayev, J., Ozgun, G., Oznur, M., Peiro Marques, F. M., Pisapia, P., Poller, D., Pyzlak, M., Robinson, B., Rossi, E. D., Roy-Chowdhuri, S., Saieg, M., Savic Prince, S., Schmitt, F. C., Javier Segui Ivanez, F., Stoos-Veic, T., Sulaieva, O., Sweeney, B. J., Tuccari, G., van Velthuysen, M. -L., Vanderlaan, P. A., Vielh, P., Viola, P., Voorham, R., Weynand, B., Zeppa, P., Faquin, W. C., Pitman, M. B., Troncone, G., Erasmus MC other, and Pathology
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Cancer Research ,Biopsy ,neoplasms ,0302 clinical medicine ,Surveys and Questionnaires ,Cytology ,Pathology ,Surveys and Questionnaire ,coronavirus disease 2019 (COVID‐ ,malignancy rate ,Societies, Medical ,Gastrointestinal tract ,Pathology, Clinical ,medicine.diagnostic_test ,stopnja malignosti ,udc:616 ,Serous fluid ,citopatologija ,Fine-needle aspiration ,Oncology ,Biliary tract ,030220 oncology & carcinogenesis ,coronavirus disease 2019 (COVID-19) ,Life Sciences & Biomedicine ,Human ,medicine.medical_specialty ,fine‐ ,Urinary system ,Biopsy, Fine-Needle ,030209 endocrinology & metabolism ,Workload ,Malignancy ,cytopathology ,fine-needle aspiration ,needle aspiration ,COVID-19 ,Communicable Disease Control ,Humans ,Laboratories, Hospital ,SARS-CoV-2 ,Hospital ,Clinical ,coronavirus disease 2019 ,03 medical and health sciences ,novotvorbe ,Medical ,Internal medicine ,medicine ,coronavirus disease 2019 (COVID-19), cytopathology, fine-needle aspiration, malignancy rate ,tankoigelna biopsija ,Science & Technology ,koronavirusna bolezen ,business.industry ,medicine.disease ,patologija ,Cytopathology ,Fine-Needle ,pathology ,Laboratories ,Societies ,19) ,business - Abstract
BACKGROUND: To the authors' knowledge, the impact of the coronavirus disease 2019 (COVID-19) pandemic on cytopathology practices worldwide has not been investigated formally. In the current study, data from 41 respondents from 23 countries were reported. METHODS: Data regarding the activity of each cytopathology laboratory during 4 weeks of COVID-19 lockdown were collected and compared with those obtained during the corresponding period in 2019. The overall number and percentage of exfoliative and fine-needle aspiration cytology samples from each anatomic site were recorded. Differences in the malignancy and suspicious rates between the 2 periods were analyzed using a meta-analytical approach. RESULTS: Overall, the sample volume was lower compared with 2019 (104,319 samples vs 190,225 samples), with an average volume reduction of 45.3% (range, 0.1%-98.0%). The percentage of samples from the cervicovaginal tract, thyroid, and anorectal region was significantly reduced (P < .05). Conversely, the percentage of samples from the urinary tract, serous cavities, breast, lymph nodes, respiratory tract, salivary glands, central nervous system, gastrointestinal tract, pancreas, liver, and biliary tract increased (P < .05). An overall increase of 5.56% (95% CI, 3.77%-7.35%) in the malignancy rate in nongynecological samples during the COVID-19 pandemic was observed. When the suspicious category was included, the overall increase was 6.95% (95% CI, 4.63%-9.27%). CONCLUSIONS: The COVID-19 pandemic resulted in a drastic reduction in the total number of cytology specimens regardless of anatomic site or specimen type. The rate of malignancy increased, reflecting the prioritization of patients with cancer who were considered to be at high risk. Prospective monitoring of the effect of delays in access to health services during the lockdown period is warranted. ispartof: CANCER CYTOPATHOLOGY vol:128 issue:12 pages:885-894 ispartof: location:United States status: published
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- 2020
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