1. Sex differences in uric acid and NT-pro BNP assessments during coronary severity
- Author
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Ximing Chen, Shixiang Wang, Zhaoqi Huang, and Guofeng Guo
- Subjects
Male ,Acute coronary syndrome ,medicine.medical_specialty ,medicine.drug_class ,Observational Study ,Coronary Artery Disease ,Coronary Angiography ,Severity of Illness Index ,acute coronary syndrome ,Coronary artery disease ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Natriuretic Peptide, Brain ,Severity of illness ,Natriuretic peptide ,sex ,Humans ,Medicine ,030212 general & internal medicine ,Aged ,Retrospective Studies ,Aged, 80 and over ,Sex Characteristics ,business.industry ,Retrospective cohort study ,General Medicine ,Middle Aged ,medicine.disease ,Peptide Fragments ,Uric Acid ,medicine.anatomical_structure ,chemistry ,NT-proBNP ,030220 oncology & carcinogenesis ,severity of coronary artery disease ,Cardiology ,Uric acid ,Female ,business ,Biomarkers ,Research Article ,Sex characteristics ,Artery - Abstract
To investigate the correlation between uric acid (UA) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and coronary artery severity in acute coronary syndrome patients of different sexes. A total of 134 patients with acute coronary syndrome (ACS) were investigated. According to sex, there were 96 cases in male group and 38 cases in female group. According to the number of diseased vessels, the degree of coronary artery lesion was determined and divided into negative group (n = 21), single vessel lesion group (n = 43), double vessel lesion group (n = 38), and 3 vessel lesion group (n = 32). Univariate analysis showed that UA, NT-proBNP was correlated with the severity of ACS (P .05). There was no significant correlation between NT-proBNP and severity of coronary artery disease in different sex (P > .05). UA was significantly correlated with the severity of coronary heart disease, especially in women, but not in men. The level of NT-proBNP was positively correlated with the severity of coronary artery, but no significant difference was found in different sexes.
- Published
- 2020
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