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1. Magnesium Perchlorate as Efficient Lewis Acid: A Simple and Convenient Route to 1,4-Dihydropyridines

Author

Paolo Melchiorre, Giuseppe Bartoli, Krzysztof Babiuch, Armando Carlone, Letizia Sambri, Patrizia Galzerano, Marcella Bosco, Bartoli G., Babiuch K., Bosco M., Carlone A., Galzerano P., Melchiorre P., and Sambri L.

Subjects
Magnesium perchlorate, Organic Chemistry, Domino reaction, Combinatorial chemistry, chemistry.chemical_compound, 1,4-dihydropyridines, Cyclization, Michael addition, chemistry, Cascade reaction, Simple (abstract algebra), Michael reaction, Lewis acids and bases, 4-dihydropyridines
Abstract

A new protocol for the synthesis of various 1,2,3,4-tetrasubstituted 1,4-dihydropyridines from enamino or carbonylic derivatives promoted by Mg(ClO 4 ) 2 is presented.

Published
2007

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