1. A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia
- Author
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Emanuele F. Osimo, Stefan P. Brugger, E. Louise Thomas, Oliver D. Howes, Medical Research Council (MRC), Osimo, Emanuele F [0000-0001-6239-5691], Thomas, E Louise [0000-0003-4235-4694], Apollo - University of Cambridge Repository, Osimo, Emanuele F. [0000-0001-6239-5691], and Thomas, E. Louise [0000-0003-4235-4694]
- Subjects
2 Aetiology ,2.3 Psychological, social and economic factors ,Prevention ,brief-communication ,32 Biomedical and Clinical Sciences ,3 Good Health and Well Being ,Serious Mental Illness ,Cardiovascular ,Brief Communication ,humanities ,3214 Pharmacology and Pharmaceutical Sciences ,Oral and gastrointestinal ,Brain Disorders ,Stroke ,631/378/340 ,Mental Health ,Clinical Research ,692/699/476/1799 ,Schizophrenia ,Biomedical Imaging ,2.1 Biological and endogenous factors ,Obesity ,Metabolic and endocrine ,Nutrition - Abstract
Funder: DH | National Institute for Health Research (NIHR); doi: https://doi.org/10.13039/501100000272, Funder: RCUK | Medical Research Council (MRC); doi: https://doi.org/10.13039/501100000265, People with schizophrenia show higher risk for abdominal obesity than the general population, which could contribute to excess mortality. However, it is unclear whether this is driven by alterations in abdominal fat partitioning. Here, we test the hypothesis that individuals with schizophrenia show a higher proportion of visceral to total body fat measured using magnetic resonance imaging (MRI). We recruited 38 participants with schizophrenia and 38 healthy controls matched on age, sex, ethnicity, and body mass index. We found no significant differences in body fat distribution between groups, suggesting that increased abdominal obesity in schizophrenia is not associated with altered fat distribution.
- Published
- 2022