1. Prescription opioid registry protocol in an integrated health system.
- Author
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Ray, G Thomas, Bahorik, Amber L, VanVeldhuisen, Paul C, Weisner, Constance M, Rubinstein, Andrea L, and Campbell, Cynthia I
- Subjects
Humans ,Analgesics ,Opioid ,Registries ,Retrospective Studies ,Algorithms ,Adult ,Aged ,Aged ,80 and over ,Middle Aged ,Delivery of Health Care ,Integrated ,California ,Female ,Male ,Drug Prescriptions ,Young Adult ,Practice Patterns ,Physicians' ,Analgesics ,Opioid ,and over ,Delivery of Health Care ,Integrated ,Practice Patterns ,Physicians' ,Health Policy & Services ,Public Health and Health Services - Abstract
ObjectivesTo establish a prescription opioid registry protocol in a large health system and to describe algorithms to characterize individuals using prescription opioids, opioid use episodes, and concurrent use of sedative/hypnotics.Study designProtocol development and retrospective cohort study.MethodsUsing Kaiser Permanente Northern California (KPNC) electronic health record data, we selected patients using prescription opioids in 2011. Opioid and sedative/hypnotic fills, and physical and psychiatric comorbidity diagnoses, were extracted for years 2008 to 2014. Algorithms were developed to identify each patient's daily opioid and sedative/hypnotic use, and morphine daily-dose equivalent. Opioid episodes were classified as long-term, episodic, or acute. Logistic regression was used to predict characteristics associated with becoming a long-term opioid user.ResultsIn 2011, 18% of KPNC adult members filled at least 1 opioid prescription. Among those patients, 25% used opioids long term and their average duration of use was more than 4 years. Sedative/hypnotics were used by 76% of long-term users. Being older, white, living in a more deprived neighborhood, having a chronic pain diagnosis, and use of sedative/hypnotics were predictors of initiating long-term opioid use.ConclusionsThis study established a population-based opioid registry that is flexible and can be used to address important questions of prescription opioid use. It will be used in future studies to answer a broad range of other critical public health issues relating to prescription opioid use.
- Published
- 2017