14 results on '"Postoperative pulmonary complication"'
Search Results
2. Use of Noninvasive Ventilation in Postoperative Patients in Abdominal Surgery
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Alessandri, Francesco, Albante, Alida, Giordano, Giovanni, Pugliese, Francesco, and Esquinas, Antonio M., editor
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- 2023
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3. Effect of goal-directed fluid therapy based on plasma colloid osmotic pressure on the postoperative pulmonary complications of older patients undergoing major abdominal surgery.
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Feng, Anqi, Lu, Pan, Yang, Yanan, Liu, Ying, Ma, Lei, and Lv, Jianrui
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FLUID therapy , *OSMOTIC pressure , *OLDER patients , *ABDOMINAL surgery , *SURGICAL complications , *GOAL (Psychology) - Abstract
Background: As an important component of accelerated rehabilitation surgery, goal-directed fluid therapy (GDT) is one of the optimized fluid therapy strategies and is closely related to perioperative complications and mortality. This article aimed to study the effect of combining plasma colloid osmotic pressure (COP) with stroke volume variation (SVV) as a target for intraoperative GDT for postoperative pulmonary complications in older patients undergoing major abdominal surgery. Methods: In this study, older patients (n = 100) undergoing radical resection of gastroenteric tumors were randomized to three groups: Group C (n1 = 31) received a conventional infusion regimen, Group S1 (n2 = 34) received GDT based on SVV, and Group S2 (n3 = 35) received GDT based on SVV and COP. The results were recorded, including the lung injury score (LIS); PaO2/FiO2 ratio; lactic acid value at the times of beginning (T0) and 1 h (T1), 2 h (T2), and 3 h (T3) after liquid infusion in the operation room; the total liquid infusion volume; infusion volumes of crystalline and colloidal liquids; urine production rate; pulmonary complications 7 days after surgery; and the severity grading of postoperative pulmonary complications. Results: The patients in the S2 group had fewer postoperative pulmonary complications than those in the C group (P < 0.05) and the proportion of pulmonary complications of grade 1 and higher than grade 2 in S2 group was significantly lower than that in C group (P <0.05); the patients in the S2 group had a higher PaO2/FiO2 ratio than those in the C group (P < 0.05), lower LIS than those in the S1 and C groups (P < 0.05), less total liquid infusion than those in the C group (P < 0.05), and more colloidal fluid infusion than those in the S1 and C groups (P < 0.05). Conclusion: The findings of our study show that intraoperative GDT based on COP and SVV can reduce the incidence of pulmonary complications and conducive to shortening the hospital stay in older patients after gastrointestinal surgery. Trial registration: Chinese Clinical Trial. no. ChiCTR2100045671. Registry at www.chictr.org.cn on April 20, 2021. [ABSTRACT FROM AUTHOR]
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- 2023
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4. Laparoskopik Majör Abdominal Kanser Cerrahisi Sonrası Postoperatif Pulmoner Komplikasyonların Öngörülmesinde ASA ve ARİSCAT Risk İndeksinin Değerlendirilmesi.
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Küçük, Kubilay, Kaya, Menşure, Kalaycı, Dilek, Aşkın, Tuğba, and Şen, Özlem
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HOSPITAL admission & discharge , *SURGICAL site , *ABDOMINAL surgery , *LENGTH of stay in hospitals , *MEDICAL ethics committees , *PNEUMOPERITONEUM , *SURGICAL site infections , *RECTAL surgery - Abstract
Objective:Postoperative pulmonary complications (PPC) are one of the most important causes of postoperative morbidity and mortality. The ARISCAT Risk Index is a seven-variable regression model that classifies patients as low, intermediate, and high risk and is used to estimate the overall incidence of postoperative pulmonary complications. In our study, we aimed to evaluate the effectiveness of ASA and ARISCAT index in predicting pulmonary complications in after laparoscopic abdominal cancer surgery. Materials and Method:After the approval of Hospital Ethics Committee, 100 patients scheduled to have major laparoscopic abdominal cancer surgery were included in the study. Preoperative ASA and ARISCAT score, comorbidities, intraoperative fluid amount, ventilation parameters, pneumoperitoneum pressure and duration of surgery were recorded. Patients were followed up for pulmonary complications until discharge from hospital. The length of hospital stay was recorded. Results:Pulmonary complications developed in 11 patients postoperatively. PPC incidence was found similiar within ASA and ARISCAT risk groups (p> 0.05). There was no significant correlation between ASA and ARISCAT risk index and PPC (p= 0.23 and p= 0.89, respectively). The number of fluids administered intraoperatively was significantly higher in patients who developed PPC (p= 0.018). There was a significant correlation between sugical site and PPC development (p= 0.012). The duration of surgery and length of hospital stay was longer in patients with PPC (pË,0.05). Conclusion:We found that both ASA score and ARISCAT risk index are not sufficient to predict postoperative pulmonary complications in laparoscopic major abdominal cancer surgery, and the surgical site, long operation time and the volume of fluid used intraoperatively are important independent risk factors for pulmonary complications. [ABSTRACT FROM AUTHOR]
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- 2022
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5. Recruitment Maneuver to Reduce Postoperative Pulmonary Complications after Laparoscopic Abdominal Surgery: A Systematic Review and Meta-Analysis.
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Pei, Shuaijie, Wei, Wei, Yang, Kai, Yang, Yiyi, Pan, Yu, Wei, Jinrui, Yao, Shanglong, and Xia, Haifa
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ARTIFICIAL respiration , *ABDOMINAL surgery , *SURGICAL complications , *LAPAROSCOPIC surgery , *PATIENT selection , *RESPIRATORY mechanics - Abstract
Background: Lung-protective ventilation strategies are recommended for patients undergoing mechanical ventilation. However, there are currently no guidelines to follow regarding recruitment maneuvers (RMs). We attempted to identify the effects of RMs on patients undergoing laparoscopic abdominal surgery. Methods: We searched for randomized controlled trials (RCTs) in PubMed, the Cochrane Library databases, Embase, Web of Science and the ClinicalTrials.gov registry for trials published up to December 2021. The primary outcome was postoperative pulmonary complications (PPCs). The secondary outcomes consisted of the static lung compliance, driving pressure (DP), intraoperative oxygenation index (OI), OI in the post-anesthesia care unit (PACU), mean arterial pressure (MAP) and heart rate (HR). Seventeen RCTs with a total of 3480 patients were examined. Results: Patients who received RMs showed a considerable reduction in PPCs (risk ratio (RR) = 0.70; 95% confidence interval (CI): 0.62 to 0.79; p < 0.01), lower DP (weighted mean difference (WMD) = −3.96; 95% CI: −5.97 to −1.95; p < 0.01), elevated static lung compliance (WMD = 10.42; 95% CI: 6.13 to 14.71; p < 0.01) and improved OI (intraoperative: WMD = 53.54; 95% CI: 21.77 to 85.31; p < 0.01; PACU: WMD = 59.40; 95% CI: 39.10 to 79.69; p < 0.01) without substantial changes in MAP (WMD = −0.16; 95% CI −1.35 to 1.03; p > 0.05) and HR (WMD = −1.10; 95% CI: −2.29 to 0.10; p > 0.05). Conclusions: Recruitment maneuvers reduce postoperative pulmonary complications and improve respiratory mechanics and oxygenation in patients undergoing laparoscopic abdominal surgery. More data are needed to elucidate the effect of recruitment maneuver on the circulatory system. [ABSTRACT FROM AUTHOR]
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- 2022
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6. Prehabilitation and education in major abdominal and thoracic surgery reduces length of stay and ventilation days.
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Hassan, Anwar, Boyle, Shelley, Lai, William, Barve, Kirti, Scanlon, Katherine, Shakeshaft, Anthony J., and Cox, Michael R.
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ABDOMINAL surgery ,LENGTH of stay in hospitals ,CONFIDENCE intervals ,THORACIC surgery ,HEALTH outcome assessment ,FISHER exact test ,ARTIFICIAL respiration ,T-test (Statistics) ,DESCRIPTIVE statistics ,QUESTIONNAIRES ,CHI-squared test ,PREHABILITATION ,PATIENT education ,ODDS ratio - Abstract
INTRODUCTION: Poor cardiopulmonary fitness is associated with an increased risk of morbidity and mortality following major surgery. Targeted prehabilitation interventions with adequate intensity improve cardiopulmonary function. Several systematic reviews have noted the variation in outcomes for prehabilitation, providing poor evidence due to inadequate patient numbers and poor compliance. Our aim was to assess the outcomes of the Preoperative Education and Prehabilitation Program (PrEPP) for patients undergoing major abdominal or thoracic surgery. METHODS: PrEPP is a supervised education and exercise training program twice a week and an at-home exercise program three times a week for up to four weeks. A comparison of outcomes was made using the data collected on each patient in PrEPP with a historical control group. RESULTS: There were 370 patients, 185 in each group. They were matched for age (+/- 10 years), gender, and surgery type. There were significant reductions in prolonged ventilation (>48 hours) from 5.4% to 1.1% (p = 0.03) and mean length of stay (LOS) from 10.2 days to 8.5 days (p = 0.04) in the PrEPP group. The incidence of superficial surgical site infection was also found to be less in the PrEPP group (p = 0.02). There were no significant differences in the incidence of pneumonia (3.8% to 2.7%), unplanned re-intubation (3.8% to 1.6%), readmission rate (12.4% to 9.7%), cardiac events or other post-surgical infections. CONCLUSION: The PrEPP was associated with reduced ventilation days and LOS. Further studies are required to confirm these results. [ABSTRACT FROM AUTHOR]
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- 2022
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7. ICEAGE (Incidence of Complications following Emergency Abdominal surgery: Get Exercising): study protocol of a pragmatic, multicentre, randomised controlled trial testing physiotherapy for the prevention of complications and improved physical recovery after emergency abdominal surgery
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Ianthe Boden, Kate Sullivan, Claire Hackett, Brooke Winzer, Rebecca Lane, Melissa McKinnon, and Iain Robertson
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Emergency surgery ,Abdominal surgery ,Complications ,Physiotherapy ,Breathing exercises ,Postoperative pulmonary complication ,Surgery ,RD1-811 ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Abstract Background Postoperative complications and delayed physical recovery are significant problems following emergency abdominal surgery. Physiotherapy aims to aid recovery and prevent complications in the acute phase after surgery and is commonplace in most first-world hospitals. Despite ubiquitous service provision, no well-designed, adequately powered, parallel-group, randomised controlled trial has investigated the effect of physiotherapy on the incidence of respiratory complications, paralytic ileus, rate of physical recovery, ongoing need for formal sub-acute rehabilitation, hospital length of stay, health-related quality of life, and mortality following emergency abdominal surgery. We hypothesise that an enhanced physiotherapy care package of additional education, breathing exercises, and early rehabilitation prevents postoperative complications and improves physical recovery following emergency abdominal surgery compared to standard care alone. Methods The Incidence of Complications following Emergency Abdominal surgery: Get Exercising (ICEAGE) trial is a pragmatic, investigator-initiated, multicentre, patient- and assessor-blinded, parallel-group, active-placebo controlled randomised trial, powered for superiority. ICEAGE will compare standard care physiotherapy to an enhanced physiotherapy care package in 288 participants admitted for emergency abdominal surgery at three Australian hospitals. Participants will be randomised using concealed allocation to receive either standard care physiotherapy (education, single session of coached breathing exercises, and daily early ambulation for 15 min) or an enhanced physiotherapy care package (education, twice daily coached breathing exercises for a minimum 2 days, and 30 min of daily supervised early rehabilitation for minimum five postoperative days). The primary outcome is a respiratory complication within the first 14 postoperative hospital days assessed daily with standardised diagnostic criteria. Secondary outcomes include referral for sub-acute rehabilitation services, discharge destination, paralytic ileus, hospital length of stay and costs, intensive care unit utilisation, 90-day patient-reported complications and health-related quality of life and physical capacity, and mortality at 30 days and at 1 year following surgery. Discussion The morbidity, mortality, and fiscal burdens following emergency abdominal surgery are some of the worst within surgery. Physiotherapy may be an effective, low-cost, minimal harm intervention to improve outcomes and reduce hospital utilisation following this surgery type. ICEAGE will test the benefits of this commonly provided intervention within a methodologically robust, multicentre, double-blinded, active-placebo controlled randomised trial. Trial registration ACTRN 12615000318583. Registered 8 April 2015
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- 2018
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8. Comparison of Postoperative Pulmonary Complication Indices in Elective Abdominal Surgery Patients.
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Gülsen, Askin, Kilinc, Oguz, Tertemiz, Kemal Can, Ekice, Tuncay, and Günay, Türkan
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ABDOMINAL surgery , *ELECTIVE surgery , *SURGICAL complications , *ARTIFICIAL respiration , *NONINVASIVE ventilation , *RESPIRATORY insufficiency - Abstract
Background: Postoperative pulmonary complications (PPC) are important problems that prolong hospital stays by increasing morbidity and mortality of patients. Early identification of risky cases through preoperative evaluation is important for reducing the complications that may be seen in patients postoperatively. The aim of this study is to calculate, evaluate and compare the risk indices for PPC in patients who will undergo elective abdominal surgery. Materials and Methods: One hundred twenty-four patients who were hospitalized for elective abdominal surgery were included in this prospective observational study. American Society of Anesthesiologists (ASA), Epstein and Shapiro scores, respiratory failure index (RFI), pneumonia risk indexes (PI) and scores were calculated preoperatively. Patients were re-evaluated at the 48th postoperative hour, and one-week follow-up was performed. The patients with PPCs are recorded. Results: The mean PPC rate was 36.8%. Based on this, pleural effusion was observed in 18.5%, prolonged mechanical ventilation in 8.9%, atelectasis in 9.7%, and respiratory failure in 5.7%, bronchospasm in 4.0%, and pneumonia in 3.2% of patients. An increased risk in PPC was determined if ASA were above 3 (odds ratio, [OR], 7.06; <0.001), PI scores were above 3 (OR, 6.67; <0.001), RFI score were above 4 (OR, 6.30, p:0.001) and Shapiro score above 2 (OR, 20.01; <0.001), respectively. Conclusion: The Shapiro index is the strongest predictor of pulmonary complications, whereas the PI is the strongest predictor of morbidity risk. However, RFI and the PI are equally valuable for predicting respiratory complications and may prove to be useful in abdominal surgeries for preoperative assessment. [ABSTRACT FROM AUTHOR]
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- 2020
9. Perioperative Noninvasive Ventilation After Adult or Pediatric Surgery: A Comprehensive Review
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Artem Kuzovlev, Giovanni Landoni, Luca Cabrini, Valery Likhvantsev, Landoni, G., Likhvantsev, V., Kuzovlev, A., and Cabrini, L.
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Adult ,medicine.medical_specialty ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,surgery ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,Pediatric surgery ,medicine ,postoperative ,Humans ,Intubation ,Respiratory function ,perioperative ,Child ,Hypoxia ,acute respiratory failure ,noninvasive ventilation ,postoperative pulmonary complication ,Noninvasive Ventilation ,business.industry ,Perioperative ,Respiration, Artificial ,Obesity, Morbid ,Cardiac surgery ,Anesthesiology and Pain Medicine ,Cardiothoracic surgery ,Anesthesia ,Noninvasive ventilation ,Respiratory Insufficiency ,Cardiology and Cardiovascular Medicine ,business ,Abdominal surgery - Abstract
Postoperative pulmonary complications and acute respiratory failure are among the leading causes of adverse postoperative outcomes. Noninvasive ventilation may safely and effectively prevent acute respiratory failure in high-risk patients after cardiothoracic surgery and after abdominal surgery. Moreover, noninvasive ventilation can be used to treat postoperative hypoxemia, particularly after abdominal surgery. Noninvasive ventilation also can be helpful to prevent or manage intraoperative acute respiratory failure during non-general anesthesia, primarily in patients with poor respiratory function. Finally, noninvasive ventilation is superior to standard preoxygenation in delaying desaturation during intubation in morbidly obese and in critically ill hypoxemic patients. The few available studies in children suggest that noninvasive ventilation could be safe and valuable in treating hypoxemic or hypercapnic acute respiratory failure after cardiac surgery; on the other hand, it could be dangerous after tracheoesophageal correction.
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- 2022
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10. Optimizing Prophylactic CPAP in Patients Without Obstructive Sleep Apnoea for High-Risk Abdominal Surgeries: A Meta-regression Analysis.
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Singh, Preet, Borle, Anuradha, Shah, Dipal, Sinha, Ashish, Makkar, Jeetinder, Trikha, Anjan, and Goudra, Basavana
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CONTINUOUS positive airway pressure , *ABDOMINAL surgery , *PNEUMONIA , *RISK factors of pneumonia , *PNEUMONIA treatment , *PATIENTS - Abstract
Introduction: Prophylactic continuous positive airway pressure (CPAP) can prevent pulmonary adverse events following upper abdominal surgeries. The present meta-regression evaluates and quantifies the effect of degree/duration of (CPAP) on the incidence of postoperative pulmonary events. Methods: Medical databases were searched for randomized controlled trials involving adult patients, comparing the outcome in those receiving prophylactic postoperative CPAP versus no CPAP, undergoing high-risk abdominal surgeries. Our meta-analysis evaluated the relationship between the postoperative pulmonary complications and the use of CPAP. Furthermore, meta-regression was used to quantify the effect of cumulative duration and degree of CPAP on the measured outcomes. Results: Seventy-three potentially relevant studies were identified, of which 11 had appropriate data, allowing us to compare a total of 362 and 363 patients in CPAP and control groups, respectively. Qualitatively, Odds ratio for CPAP showed protective effect for pneumonia [0.39 (0.19-0.78)], atelectasis [0.51 (0.32-0.80)] and pulmonary complications [0.37 (0.24-0.56)] with zero heterogeneity. For prevention of pulmonary complications, odds ratio was better for continuous than intermittent CPAP. Meta-regression demonstrated a positive correlation between the degree of CPAP and the incidence of pneumonia with a regression coefficient of +0.61 (95 % CI 0.02-1.21, P = 0.048, τ = 0.078, r = 7.87 %). Overall, adverse effects were similar with or without the use of CPAP. Conclusions: Prophylactic postoperative use of continuous CPAP significantly reduces the incidence of postoperative pneumonia, atelectasis and pulmonary complications in patients undergoing high-risk abdominal surgeries. Quantitatively, increasing the CPAP levels does not necessarily enhance the protective effect against pneumonia. Instead, protective effect diminishes with increasing degree of CPAP. [ABSTRACT FROM AUTHOR]
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- 2016
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11. Driving Pressure During General Anesthesia for Open Abdominal Surgery (DESIGNATION): study protocol of a randomized clinical trial
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Hol, Liselotte, Nijbroek, Sunny G. L. H., Neto, Ary Serpa, de Abreu, Marcelo Gama, Pelosi, Paolo, Hemmes, Sabrine N. T., Aarts, Leon P. H. J., Akkerman, Ronald D. L., Albersen, Juliette J. E., Aurilio, Caterina, Battaglini, Denise, de Boer, Hans D., Boom, Annemieke, Boer, Christa, Brouwer, Tammo, Buhre, Wolfgang F. F. A., Bulte, Carolina S. E., Edward-Rutten, Gitara M., Godfried, Marc B., Helmerhorst, Hendrik J. F., Hofland, Jan, Hoogenboom, Hester, Ten Hoope, W., Houweling, Bernard M., Huhn, Ragnar, Konijn, Wanda, Koopman-van Gemert, Ankie W. M. M., De Korte-de Boer, Dianne J., Kortekaas, Minke C., Van Lier, Felix, Preckel, Benedikt, Rad, Mandana, Sansone, Pasquale, Stamkot, Andre, Stolker, Robert Jan, Thiel, Bram, Ubben, Johannes F. H., Struys, Michel, In 't Veld, Bastiaan A., Wrigge, Hermann, Zeillemaker-Hoekstra, Miriam, van der Zwan, Tim, Zwijsen, Johannes H. M. J., Hollmann, Markus W., Schultz, Marcus J., Anesthesiology, ACS - Diabetes & metabolism, Hol, L, Nijbroek, Sglh, Neto, A, de Abreu, Mg, Pelosi, P, Hemmes, Snt, Aarts, Lphj, Akkerman, Rdl, Albersen, Jje, Aurilio, C, Battaglini, D, de Boer, Hd, Boom, A, Boer, C, Brouwer, T, Buhre, Wffa, Bulte, Cse, Edward-Rutten, Gm, Godfried, Mb, Helmerhorst, Hjf, Hofland, J, Hoogenboom, H, Ten Hoope, W, Houweling, Bm, Huhn, R, Konijn, W, Koopman-van Gemert, Awmm, De Korte-de Boer, Dj, Kortekaas, Mc, van Lier, F, Preckel, B, Rad, M, Sansone, P, Stamkot, A, Stolker, Rj, Thiel, B, Ubben, Jfh, Struys, Mmrf, 't Veld, Bai, Wrigge, H, Zeillemaker-Hoekstra, M, van der Zwan, T, Zwijsen, Jhmj, Hollmann, Mw, Schultz, Mj, MUMC+: Centrum voor Acute en Kritieke Zorg (3), Anesthesiologie, MUMC+: MA Anesthesiologie (9), RS: MHeNs - R3 - Neuroscience, Graduate School, Intensive Care Medicine, APH - Quality of Care, ACS - Heart failure & arrhythmias, ACS - Pulmonary hypertension & thrombosis, ACS - Microcirculation, Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Radiotherapy, Intensive Care, and Cardiology
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Lung Diseases ,Male ,ATELECTASIS ,medicine.medical_treatment ,Medicine (miscellaneous) ,Atelectasis ,Intraoperative ventilation ,law.invention ,Positive-Pressure Respiration ,DEFINITIONS ,Study Protocol ,0302 clinical medicine ,Mechanical ventilation ,Randomized controlled trial ,030202 anesthesiology ,law ,OBESE-PATIENTS ,Clinical endpoint ,Medicine and Health Sciences ,Medicine ,Pharmacology (medical) ,END-EXPIRATORY-PRESSURE ,030212 general & internal medicine ,Tidal volume ,Postoperative pulmonary ,Randomized Controlled Trials as Topic ,Aged, 80 and over ,lcsh:R5-920 ,Postoperative pulmonary complications ,Delta P ,Positive end-expiratory pressure ,Abdominal Cavity ,Pulmonary ,Middle Aged ,respiratory system ,Treatment Outcome ,Recruitment maneuver ,Anesthesia ,Surgical Procedures, Operative ,Breathing ,Female ,lcsh:Medicine (General) ,therapeutics ,Compliance ,circulatory and respiratory physiology ,Adult ,Pulmonary complication ,ΔP ,complications ,Anesthesia, General ,03 medical and health sciences ,Young Adult ,Postoperative complications ,Double-Blind Method ,Tidal Volume ,Humans ,LOW-TIDAL-VOLUME ,Aged ,POSTOPERATIVE PULMONARY COMPLICATIONS ,business.industry ,CHEST-WALL MECHANICS ,medicine.disease ,PREVENTION ,Postoperative complication ,PROTECTIVE MECHANICAL VENTILATION ,respiratory tract diseases ,Pulmonary complications ,business ,Postoperative pulmonary complication ,LUNG ,Abdominal surgery - Abstract
BackgroundIntraoperative driving pressure (ΔP) is associated with development of postoperative pulmonary complications (PPC). When tidal volume (VT) is kept constant, ΔP may change according to positive end-expiratory pressure (PEEP)-induced changes in lung aeration. ΔP may decrease if PEEP leads to a recruitment of collapsed lung tissue but will increase if PEEP mainly causes pulmonary overdistension. This study tests the hypothesis that individualized high PEEP, when compared to fixed low PEEP, protects against PPC in patients undergoing open abdominal surgery.MethodsThe “Driving prESsure durIng GeNeral AnesThesIa for Open abdomiNal surgery trial” (DESIGNATION) is an international, multicenter, two-group, double-blind randomized clinical superiority trial. A total of 1468 patients will be randomly assigned to one of the two intraoperative ventilation strategies. Investigators screen patients aged ≥ 18 years and with a body mass index ≤ 40 kg/m2, scheduled for open abdominal surgery and at risk for PPC. Patients either receive an intraoperative ventilation strategy with individualized high PEEP with recruitment maneuvers (RM) (“individualized high PEEP”) or one in which PEEP of 5 cm H2O without RM is used (“low PEEP”). In the “individualized high PEEP” group, PEEP is set at the level at which ΔP is lowest. In both groups of the trial, VTis kept at 8 mL/kg predicted body weight. The primary endpoint is the occurrence of PPC, recorded as a collapsed composite of adverse pulmonary events.DiscussionDESIGNATION will be the first randomized clinical trial that is adequately powered to compare the effects of individualized high PEEP with RM versus fixed low PEEP without RM on the occurrence of PPC after open abdominal surgery. The results of DESIGNATION will support anesthesiologists in their decisions regarding PEEP settings during open abdominal surgery.Trial registrationClinicaltrials.gov,NCT03884543. Registered on 21 March 2019.
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- 2020
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12. ICEAGE (Incidence of Complications following Emergency Abdominal surgery: Get Exercising): study protocol of a pragmatic, multicentre, randomised controlled trial testing physiotherapy for the prevention of complications and improved physical recovery after emergency abdominal surgery
- Author
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Iain K Robertson, Rebecca Lane, Brooke Winzer, Ianthe Boden, Kate Sullivan, Melissa McKinnon, and Claire Hackett
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medicine.medical_specialty ,Complications ,Referral ,Ileus ,medicine.medical_treatment ,lcsh:Surgery ,Abdominal surgery ,030230 surgery ,law.invention ,03 medical and health sciences ,Study Protocol ,0302 clinical medicine ,Randomized controlled trial ,Quality of life ,Breathing exercises ,law ,medicine ,Humans ,030212 general & internal medicine ,Intraoperative Complications ,Physiotherapy ,Digestive System Surgical Procedures ,Early Ambulation ,Physical Therapy Modalities ,Rehabilitation ,business.industry ,Incidence ,Australia ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,Pneumonia ,Patient education ,lcsh:RD1-811 ,lcsh:RC86-88.9 ,Length of Stay ,medicine.disease ,Intensive care unit ,Exercise Therapy ,Treatment Outcome ,Emergency Medicine ,Physical therapy ,Quality of Life ,Emergency surgery ,Surgery ,business ,Postoperative pulmonary complication - Abstract
Background Postoperative complications and delayed physical recovery are significant problems following emergency abdominal surgery. Physiotherapy aims to aid recovery and prevent complications in the acute phase after surgery and is commonplace in most first-world hospitals. Despite ubiquitous service provision, no well-designed, adequately powered, parallel-group, randomised controlled trial has investigated the effect of physiotherapy on the incidence of respiratory complications, paralytic ileus, rate of physical recovery, ongoing need for formal sub-acute rehabilitation, hospital length of stay, health-related quality of life, and mortality following emergency abdominal surgery. We hypothesise that an enhanced physiotherapy care package of additional education, breathing exercises, and early rehabilitation prevents postoperative complications and improves physical recovery following emergency abdominal surgery compared to standard care alone. Methods The Incidence of Complications following Emergency Abdominal surgery: Get Exercising (ICEAGE) trial is a pragmatic, investigator-initiated, multicentre, patient- and assessor-blinded, parallel-group, active-placebo controlled randomised trial, powered for superiority. ICEAGE will compare standard care physiotherapy to an enhanced physiotherapy care package in 288 participants admitted for emergency abdominal surgery at three Australian hospitals. Participants will be randomised using concealed allocation to receive either standard care physiotherapy (education, single session of coached breathing exercises, and daily early ambulation for 15 min) or an enhanced physiotherapy care package (education, twice daily coached breathing exercises for a minimum 2 days, and 30 min of daily supervised early rehabilitation for minimum five postoperative days). The primary outcome is a respiratory complication within the first 14 postoperative hospital days assessed daily with standardised diagnostic criteria. Secondary outcomes include referral for sub-acute rehabilitation services, discharge destination, paralytic ileus, hospital length of stay and costs, intensive care unit utilisation, 90-day patient-reported complications and health-related quality of life and physical capacity, and mortality at 30 days and at 1 year following surgery. Discussion The morbidity, mortality, and fiscal burdens following emergency abdominal surgery are some of the worst within surgery. Physiotherapy may be an effective, low-cost, minimal harm intervention to improve outcomes and reduce hospital utilisation following this surgery type. ICEAGE will test the benefits of this commonly provided intervention within a methodologically robust, multicentre, double-blinded, active-placebo controlled randomised trial. Trial registration ACTRN 12615000318583. Registered 8 April 2015 Electronic supplementary material The online version of this article (10.1186/s13017-018-0189-y) contains supplementary material, which is available to authorized users.
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- 2018
- Full Text
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13. RISK FACTORS FOR POSTOPERATIVE PULMONARY COMPLICATIONS IN UPPER ABDOMINAL SURGERY.
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Kanat, Fikret, Golcuk, Ayse, Teke, Turgut, and Golcuk, Murat
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POSTOPERATIVE care , *LUNG diseases , *PULMONARY function tests , *ABDOMINAL surgery , *SURGICAL therapeutics , *POST anesthesia nursing - Abstract
Background: Pulmonary complications are the most frequent cause of postoperative morbidity and mortality in upper abdominal surgery (UAS). We aimed to examine the influence of possible preoperative, operative and postoperative risk factors on the development of early postoperative pulmonary complications (POPC) after UAS. Methods: A prospective study of 60 consecutive patients was conducted who underwent elective UAS in general surgical unit. Each patient’s preoperative respiratory status was assessed by an experienced chest physician using clinical examination, chest radiographs, spirometry and blood gas analysis . Anaesthetical risks, surgical indications, operation time, incision type, duration of nasogastric catheter and mobilization time were noted. Forty-eight hours after the operation, pulmonary examinations of the patients were repeated. Results: Postoperative pulmonary complications were observed in 35 patients (58.3%). The most common complication was pneumonia, followed by pneumonitis, atelectasis, bronchitis, pulmonary emboli and acute respiratory failure. The presence of preoperative respiratory symptoms and the spirometric parameter of forced expiratory volume in 1 s/forced vital capacity were the most valuable risk factors for early prediction of POPC. The sensitivity, specificity and diagnostic efficiency of the presence of preoperative respiratory symptoms in the POPC prediction were 70, 61 and 66%, respectively. Conclusion: We recommend a detailed pulmonary examination and spirometry in patients who will undergo UAS by chest physicians to identify the patients at high risk for POPC, to manage respiratory problems of the patients before surgery and also to help surgeons to take early measures in such patients before a most likely POPC occurrence. Improvement of lung function in those patients at risk for POPC before operation may decrease morbidity in surgical patients. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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14. ICEAGE (Incidence of Complications following Emergency Abdominal surgery: Get Exercising): study protocol of a pragmatic, multicentre, randomised controlled trial testing physiotherapy for the prevention of complications and improved physical recovery after emergency abdominal surgery
- Author
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Boden, Ianthe, Sullivan, Kate, Hackett, Claire, Winzer, Brooke, Lane, Rebecca, McKinnon, Melissa, and Robertson, Iain
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- 2018
- Full Text
- View/download PDF
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