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This paper introduces a novel multi-classification technique, which improves two conflicting main objectives of classification problems, i.e., classification accuracy and worst case sensitivity. Global performance measures such as overall accuracy might not be enough to evaluate classifiers and alternative measurements are essentially required. This paper addresses a new model selection problem to construct a tree-based hierarchical classification model based on ensemble of six different classifiers. In our proposed approach, the model selection is tackled as a multi-objective optimization, which not only considers the accuracy of the classification, but also tries to maximize the worst case sensitivity of the multi-class problem. The proposed technique is applied on nine different classes corresponding to various breathing disorders for designing a wearable remote monitoring system. This model correctly classified the respiratory patterns of ten subjects with an accuracy of 99.25% and a sensitivity of 97.78% with detecting the changes in the anterior-posterior diameter of the chest wall during breathing function by means of two accelerometer sensors worn on subject’s rib cage and abdomen. The effects of the number of sensors, sensor placement, as well as feature selection on the classification performance are also discussed. [ABSTRACT FROM PUBLISHER]

Respiratory disorder is a highly prevalent condition associated with many adverse health problems. As the current means of diagnosis are obtrusive and ill-suited for real-time m-health applications, we explore a convenient and low-cost automatic approach that uses wearable microelectromechanical system sensor technology. The proposed system introduces the use of motion sensors to detect the changes in the anterior–posterior diameter of the chest wall during breathing function as well as extracting the informative respiratory features to be used for breathing disorders classification. Extensive evaluations are provided on six well-known classifiers with novel feature extraction techniques to distinguish among eight different pathological breathing patterns. The effects of the number of sensors, sensor placement, as well as feature selection on the classification performance are discussed. The experimental results conducted with ten subjects show the best accuracy rates of 97.50% by support vector machine and 97.37% with decision tree bagging (DTB) with all features and after feature selection, correspondingly. Furthermore, a binary classification is proposed for distinguishing between healthy people and patients with breath problems. The different assessments of classification parameters are provided by measuring the accuracy, sensitivity, specificity, F1-score and Mathew correlation coefficient. The accuracy rates above 98% suggest superior performance of DTB in binary recognition supported by the suggested new features. [ABSTRACT FROM PUBLISHER]

The measurement of human respiratory signals is crucial in cyberbiological systems. A disordered breathing pattern can be the first symptom of different physiological, mechanical, or psychological dysfunctions. Therefore, a real-time monitoring of the respiration patterns, as well as respiration rate is a critical need in medical applications. There are several methods for respiration rate measurement. However, despite their accuracy, these methods are expensive and could not be integrated in a body sensor network. In this work, we present a real-time cloud-based platform for both monitoring the respiration rate and breath pattern classification, remotely. The proposed system is designed particularly for patients with breathing problems (e.g., respiratory complications after surgery) or sleep disorders. Our system includes calibrated accelerometer sensor, Bluetooth Low Energy (BLE) and cloud-computing model. We also suggest a procedure to improve the accuracy of respiration rate for patients at rest positions. The overall error in the respiration rate calculation is obtained 0.53% considering SPR-BTA spirometer as the reference. Five types of respiration disorders, Bradapnea, Tachypnea, Cheyn-stokes, Kaussmal, and Biot's breathing are classified based on hierarchical Support Vector Machine (SVM) with seven different features. We have evaluated the performance of the proposed classification while it is individualized to every subject (case 1) as well as considering all subjects (case 2). Since the selection of kernel function is a key factor to decide SVM's performance, in this paper three different kernel functions are evaluated. The experiments are conducted with 11 subjects and the average accuracy of 94.52% for case 1 and the accuracy of 81.29% for case 2 are achieved based on Radial Basis Function (RBF). Finally, a performance evaluation has been done for normal and impaired subjects considering sensitivity, specificity and G-mean parameters of different kernel functions. [ABSTRACT FROM AUTHOR]