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Objective: Verification of the herbal plants by latest scientific tools toward understanding the molecular mechanism underlying their medicinal role is the need of the hour. Methods: Gas chromatography-mass spectrometry study of water extracts of the leaves of one herbal plant, Aristolochia indica was undertaken by standard procedures and its medicinal activity was verified with the biomolecules present in it. Results: The presence of some important biomolecules such as 2-propenoic acid, ethenyl ester, oxalic acid, cyclobutyl ethyl ester, phosphoric acid, 2-chloroethenyl dimethyl ester, pentanoic acid, 2-methylcyclohexyl ester, cis-, butylphosphonic acid, butyl cyclohexylmethyl ester, octadecanoic acid, 2,3-dihydroxypropyl ester, acetic acid, cesium salt and 2-Fluoro-6-trifluoromethylbenzoic acid, 4-nitrophenyl ester, and some others indicate represents the medicinal roles of this plant as is reported ethnopharmacologically. Conclusions: The results and discussion above clearly indicate that the various molecules present in A. indica leaf extracts do have medicinal roles ascribed to it and further work in this regard is on. [ABSTRACT FROM AUTHOR]

Introduction: The present work deals with the gas chromatography–mass spectrometry (GC-MS) analysis of Kutajarishtam which is used in the treatment of diarrhea, dysentery, irritable bowel syndrome, Crohn’s disease, hemorrhoids, etc. Materials and Methods: Kutajarishtam was bought from a standard Ayurvedic vendor at Chennai and subjected to GC-MS analysis by standard procedures. The medicinal roles of the biomolecules indicated in the GC-MS profile were screened for their various medicinal roles using Dr. Duke’s Phytochemical and ethnobotanical data and other data. Results: GC-MS profile of Kutajarishtam indicated the presence of important biomolecules such aso-Acetyl-L-serine, 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-, 2-Furanethanol., beta.-ethoxy-, Acetic acid, 1-(2-hydroxy-1-methyl-ethyl)-3-methoxymethoxy-2-methyl-propyl ester and Cyclohexan-1,4,5-triol-3-one-1-carboxylic acid which have medicinal roles which correlated well with that of Kutajarishtam. Conclusions: It is concluded that Kutajarishtam, which is an important Ayurvedic medicine, contains some very important molecules showing its efficacy. Further research is required for a better understanding of the medicinal roles of this medicine. [ABSTRACT FROM AUTHOR]

Objective: The scientific validation of ethnopharmacologically important herbal plants by latest techniques is necessary to understand their medicinal efficacy. Methods: Gas chromatography-mass spectrometry study of one herbal plant, Dodonaea viscosa var. angustifolia was undertaken by standard procedures and its medicinal activity was verified with the biomolecules present in it. Results: The presence of some important biomolecules such as catechol, N-benzyl-2-phenethylamine, acetic acid, 4-oxocyclohexyl ester, 4-amino-3-mercapto-1,2,4-triazole, 1,1'-methylene-bis(di-2-propenylamine), inositol, alanine, N-methyl-N-methoxycarbonyl-, hexyl ester, 1,3-dioxolane, 2-methyl-2-pentyl-, cyclohexane, 1-methyl-3-(1-methylethenyl)-, cis-, phthalic acid, di(2,3-dimethylphenyl) ester, heptafluorobutyric acid, 2-naphthyl ester, and 2-fluoro-6- trifluoromethylbenzoic acid, 4-nitrophenyl ester has biochemical properties which represent the ethnomedicinal roles of this plant. Conclusions: The presence of these biomolecules having medicinal properties supports the validity of the medicinal roles of D. viscosa var. angustifolia. [ABSTRACT FROM AUTHOR]