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Your search keyword '"Kuball, Jürgen H E"' showing total 1 results
Start Over Author "Kuball, Jürgen H E" Topic aciclovir
1 results on '"Kuball, Jürgen H E"'

1. Reactivation of Multidrug-Resistant HSV-1 in a Post–Allogenic Hematopoietic Stem Cell Transplant Patient: Dynamic Detection of the Rare A605V Mutation by Next-Generation Sequencing.

Author

Zheng, Shuxuan, Rümke, Lidewij L W, Rubio, Bruno Tello, Rogers, Malbert R C, Sluis, Geerte L van, Kuball, Jürgen H E, Riezebos-Brilman, Annelies, Lebbink, Robert Jan, and Lunel, Frans M Verduyn

Subjects
HEMATOPOIETIC stem cells, STEM cell transplantation, NUCLEOTIDE sequencing, HUMAN herpesvirus 1, VIRAL DNA
Abstract

We present an immunocompromised patient with a multiresistant herpes simplex virus–1 reactivation with a rare mutation (A605V) in the viral DNA polymerase gene. Next-generation sequencing suggests the presence of multiple drug-resistant strains before treatment and altered ratios during treatment, affecting the clinical response to aciclovir and foscarnet. [ABSTRACT FROM AUTHOR]

Published
2024
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