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In this paper, we present our approach for using EEG signals to activate safety measures of a robot when an error or unexpected event is perceived by the human operator. In particular, we consider brain-based error perception while the operator passively observes the robot performing an action. Our approach consists of monitoring EEG signals and detecting a brain potential called error related negativity (ERN) that spontaneously occurs when the operator perceives an error made by the robot or when an unexpected event occurs. We detect ERN by pre-training two linear classifiers using data collected from a preliminary experiment based on a visual reaction task. We derive the probability of failure in demand (PFD), commonly used to assess functional safety for a two-channel verification system based on the combination of linear classifiers. Functional safety analysis was then performed on a BMI-based robotic framework in which a signal was sent to the robot to active its safety measures in when an ERN was detected. Using brain-based signals, we demonstrate that it is possible to send an emergency stop action during mobile navigation task when unexpected events occur with an accuracy of 75%. [ABSTRACT FROM PUBLISHER]