1. Pattern of Acute Retinal Necrosis in a Referral Center in Tunisia, North Africa.
- Author
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Khochtali, Sana, Abroug, Nesrine, Kahloun, Rim, Ksiaa, Imen, Nahdi, Imen, Zaouali, Sonia, Ben Yahia, Salim, and Khairallah, Moncef
- Subjects
RETINAL diseases ,NECROSIS ,POLYMERASE chain reaction ,AQUEOUS humor ,RETINAL detachment ,DNA analysis ,HERPES simplex ,HERPESVIRUSES ,LONGITUDINAL method ,MEDICAL referrals ,OPHTHALMIC zoster ,DISEASE incidence ,RETROSPECTIVE studies ,VIRAL eye infections ,DISEASE complications - Abstract
Purpose: To describe the pattern of acute retinal necrosis (ARN) syndrome in a referral center in Tunisia.Methods: Retrospective review of the charts of 12 patients (12 eyes).Results: Necrotizing retinitis involved >50% of the retina in 33.3% of eyes. Polymerase chain reaction on aqueous humor sample identified herpes simplex virus-1 in 4 eyes (33.3%) and varicella zoster virus in 3 eyes (25%), and was negative in 5 eyes (41.7%). All patients received intravenous acyclovir, followed by oral antivirals. Follow-up ranged from 6 to 16 months. Retinal detachment (RD) occurred in 3 eyes (25%), but no patient developed bilateral ARN. Final visual acuity was 20/200 or worse in 7 eyes (58.3%). Delay in diagnosis (p = 0.015), macular involvement (p = 0.045), development of RD (p = 0.018), and 25-50% of retinal involvement (p = 0.045) were associated with a worse visual outcome.Conclusion: ARN carries poor visual prognosis in Tunisia. [ABSTRACT FROM AUTHOR]- Published
- 2015
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