1. Synthesis of Oil-Soluble Aliphatic Acylated Epicatechin and their Free Radical Scavenging Activity
- Author
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Xi Yue Li, Can Chen, Ya Nan Jia, Zhe Gao, Xiao Hu Kang, Ai Xia Qin, Yu Lei Pan, and Tong Cui
- Subjects
Oil soluble ,Acylation ,chemistry.chemical_compound ,Free Radical Scavenging Activity ,ABTS ,Antioxidant ,chemistry ,Polyphenol ,DPPH ,medicine.medical_treatment ,General Engineering ,medicine ,Organic chemistry - Abstract
A series of epicatechin derivatives, including 3-O-palmitoyl epicatechin, 3-O-myristoyl epicatechin, 3-O-lauroyl epicatechin, 3-O-decanoyl epicatechin and 3-O-octanoyl epicatechin, were prepared by the acylation method. Structures of these prepared products were characterized by LC/MS and1H-NMR spectroscopy. Their antioxidant activity were assessed by the methods of DPPH and ABTS free radical scavenging. The results showed that aliphatic acyl epicatechin derivatives with varying aliphatic groups were synthesized by this method. The antioxidant activity of aliphatic acyl epicatechin derivatives were better than the oil-soluble tea polyphenol and BHT, equal to TBHQ.
- Published
- 2013