1. Cancer of the gastroesophageal junction: a diagnosis, classification, and management review.
- Author
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Chevallay M, Bollschweiler E, Chandramohan SM, Schmidt T, Koch O, Demanzoni G, Mönig S, and Allum W
- Subjects
- Humans, Adenocarcinoma diagnosis, Adenocarcinoma pathology, Adenocarcinoma physiopathology, Adenocarcinoma therapy, Esophageal Neoplasms diagnosis, Esophageal Neoplasms pathology, Esophageal Neoplasms physiopathology, Esophageal Neoplasms therapy, Esophagogastric Junction pathology, Esophagogastric Junction physiopathology, Neoadjuvant Therapy methods
- Abstract
Management of gastroesophageal junction (GEJ) adenocarcinoma is a controversial topic. The rising incidence of this cancer requires a clear consensus to ensure proper management. Application of oncological principles for tumors of the esophagus or stomach is not possible because of comparative differences in the biology of GEJ adenocarcinoma, leading to different therapeutic options. Staging work-up with endoscopy, endosonography, and PET is essential to inform the choice of neoadjuvant treatment and surgical approach to GEJ adenocarcinoma. Surgery remains the only curative treatment and should be undertaken in specialized centers., (© 2018 New York Academy of Sciences.)
- Published
- 2018
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