1. [Complications and effectiveness of treatment of patients with locally advanced prostate cancer after combined radiotherapy and radical prostatectomy with postoperative radiotherapy].
- Author
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Solodky VA, Pavlov AY, Panshin GA, Tsybulsky AD, Garmash SV, Isaev TK, and Kravtsov IB
- Subjects
- Adenocarcinoma pathology, Aged, Aged, 80 and over, Erectile Dysfunction etiology, Humans, Incidence, Intraoperative Period, Iridium Radioisotopes administration & dosage, Iridium Radioisotopes adverse effects, Male, Middle Aged, Neoplasm Staging, Postoperative Period, Prostatic Neoplasms pathology, Radiotherapy, Adjuvant adverse effects, Russia, Treatment Outcome, Urinary Incontinence etiology, Adenocarcinoma radiotherapy, Adenocarcinoma surgery, Iridium Radioisotopes therapeutic use, Prostatectomy methods, Prostatic Neoplasms radiotherapy, Prostatic Neoplasms surgery
- Abstract
Treatment for prostate cancer remains a significant social problem due to the continuing trend of growth of morbidity and mortality in Russia from this disease. In recent years a real alternative to surgical treatment is radiotherapy. In treatment of locally advanced stages of prostate cancer radiotherapy plays a dominant role. At our institution from 2005 till 2011, 105 patients with locally advanced prostate cancer underwent complex and combined treatment comprising in the first group the concomitant radiotherapy with Ir-192 and the control group--radical prostatectomy followed by adjuvant remote radiotherapy. In patients treated with concomitant radiotherapy compared to the control group there were occurred fewer number of genitourinary complications according to the RTOG scale (5,8% vs. 32,7%). In patients who had undergone radical prostatectomy followed by adjuvant radiotherapy urinary incontinence was met significantly often.
- Published
- 2015