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53 results on '"Lane, M. D"'

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1. Completing the loop: neuron-adipocyte interactions and the control of energy homeostasis.

2. Insulin depletion leads to adipose-specific cell death in obese but not lean mice.

3. Modulating the transcriptional control of adipogenesis.

4. The adipose tissue/central nervous system axis.

5. Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes.

6. Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes.

7. Adipocyte differentiation. When precursors are also regulators.

8. The blockade of preadipocyte differentiation by protein-tyrosine phosphatase HA2 is reversed by vanadate.

9. Transcriptional regulation of gene expression during adipocyte differentiation.

10. Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein alpha and delta genes in 3T3-L1 adipocytes and white adipose tissue.

11. CCAAT/enhancer binding protein alpha (C/EBP alpha) undifferentiated protein: a developmentally regulated nuclear protein that binds to the C/EBP alpha gene promoter.

12. Regulated expression of an insulin-responsive glucose transporter (GLUT4) minigene in 3T3-L1 adipocytes and transgenic mice.

13. Trans-acting factors involved in adipogenic differentiation.

14. Insulin down-regulates expression of the insulin-responsive glucose transporter (GLUT4) gene: effects on transcription and mRNA turnover.

15. Identification of a transcriptional repressor down-regulated during preadipocyte differentiation.

16. Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes.

17. Cell-free transcription directed by the 422 adipose P2 gene promoter: activation by the CCAAT/enhancer binding protein.

18. Phosphotyrosyl turnover in insulin signaling. Characterization of two membrane-bound pp15 protein tyrosine phosphatases from 3T3-L1 adipocytes.

19. Mouse insulin-responsive glucose transporter gene: characterization of the gene and trans-activation by the CCAAT/enhancer binding protein.

20. Insulin stimulates fluid-phase endocytosis and exocytosis in 3T3-L1 adipocytes.

21. Kinetics of insulin receptor transit to and removal from the plasma membrane.

22. Induction of lipogenesis during differentiation in a "preadipocyte" cell line.

23. Expression of insulin receptors during preadipocyte differentiation.

24. Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase.

25. Selective changes in microsomal enzymes of triacylglycerol phosphatidylcholine, and phosphatidylethanolamine biosynthesis during differentiation of 3T3-L1 preadipocytes.

26. On the mechanism of preadipocyte differentiation. Masking of poly(ADP-ribose) synthetase activity during differentiation of 3T3-L1 preadipocytes.

27. Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein.

28. Insulin-induced down-regulation of insulin receptors in 3T3-L1 adipocytes. Altered rate of receptor inactivation.

29. Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes.

30. Loss of choleragen receptors and ganglioside upon differentiation of 3T3-L1 preadipocytes.

31. Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells.

32. Identification of phosphorylated 422(aP2) protein as pp15, the 15-kilodalton target of the insulin receptor tyrosine kinase in 3T3-L1 adipocytes.

33. Mechanism of regulation of the 422(aP2) gene by cAMP during preadipocyte differentiation.

34. Role of glycosylation in the processing of newly translated insulin proreceptor in 3T3-L1 adipocytes.

35. Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes.

36. Insulin-dependent phosphorylation of the insulin receptor-protein kinase and activation of glucose transport in 3T3-L1 adipocytes.

37. Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase.

38. Insulin and insulin-like growth factor 1 stimulate the phosphorylation on tyrosine of a 160 kDa cytosolic protein in 3T3-L1 adipocytes.

39. Role of glycosylation and protein synthesis in insulin receptor metabolism by 3T3-L1 mouse adipocytes.

40. Identification and partial purification of the insulin-responsive glucose transporter from 3T3-L1 adipocytes.

41. Insulin-activated tyrosine phosphorylation of a 15-kilodalton protein in intact 3T3-L1 adipocytes.

42. Homogeneous functional insulin receptor from 3T3-L1 adipocytes. Purification using N alpha B1-(biotinyl-epsilon-aminocaproyl)insulin and avidin-sepharose.

43. Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action.

44. Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes.

46. Alterations in cyclic AMP phosphodiesterase activities during differentiation of 3T3-L1 cells.

47. Alterations in insulin binding accompanying differentiation of 3T3-L1 preadipocytes.

48. Tissue specific expression of p422 protein, a putative lipid carrier, in mouse adipocytes.

49. Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes.

50. Studies of insulin resistance in adipocytes induced by macrophage mediator.

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