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1. Generation of Functional Human Adipose Tissue in Mice from Primed Progenitor Cells.

Author

Rojas-Rodriguez R, Lujan-Hernandez J, Min SY, DeSouza T, Teebagy P, Desai A, Tessier H, Slamin R, Siegel-Reamer L, Berg C, Baez A, Lalikos J, and Corvera S

Subjects
Adipocytes cytology, Adipose Tissue cytology, Animals, Heterografts, Humans, Male, Mesenchymal Stem Cells cytology, Mice, Mice, Nude, Adipocytes metabolism, Adipose Tissue metabolism, Cell Differentiation, Mesenchymal Stem Cell Transplantation, Mesenchymal Stem Cells metabolism
Abstract

Impact Statement: This research describes the use of human mesenchymal progenitor cells for generating functional adipose tissue in vivo in a nude mouse model. Further preclinical development of the methods and insights described in this article can lead to therapeutic use of these cells in regenerative and reconstructive medicine.

Published
2019
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