1. Effects of environmental tobacco smoke exposure on brain functioning in never‐smoking adolescents
- Author
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Dieleman, Joyce, Kleinjan, Marloes, Otten, Roy, van Schie, Hein T., Heuvelmans, Vivian, Luijten, Maartje, Leerstoel Finkenauer, Youth in Changing Cultural Contexts, Leerstoel Finkenauer, and Youth in Changing Cultural Contexts
- Subjects
Male ,medicine.medical_specialty ,Adolescent ,media_common.quotation_subject ,Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13] ,environmental tobacco smoke (ETS) exposure ,Audiology ,Electroencephalography ,050105 experimental psychology ,Tobacco smoke ,lcsh:RC321-571 ,Brain functioning ,03 medical and health sciences ,Behavioral Neuroscience ,All institutes and research themes of the Radboud University Medical Center ,0302 clinical medicine ,Tobacco Smoking ,Humans ,Medicine ,0501 psychology and cognitive sciences ,nicotine dependence ,lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry ,Evoked Potentials ,Original Research ,media_common ,Environmental tobacco smoke exposure ,Behaviour Change and Well-being ,medicine.diagnostic_test ,business.industry ,Addiction ,Smoking ,05 social sciences ,Brain maturation ,Brain ,Environmental Exposure ,ERPs ,Anticipation ,Cue reactivity ,Female ,Tobacco Smoke Pollution ,business ,Developmental Psychopathology ,psychological phenomena and processes ,030217 neurology & neurosurgery - Abstract
Introduction Brain functioning, as indexed by event‐related potentials (ERPs) representing smoking cue reactivity, inhibitory control, and reward processing, has been found to be compromised in smokers. However, whether environmental tobacco smoke (ETS) exposure in never smokers results in similar brain changes is unknown. This question is particularly relevant during adolescence, given ongoing brain maturation and a high risk of smoking initiation. The present study tested the associations between ETS exposure and ERPs reflecting cue reactivity (P3, LPP), inhibitory control (N2, P3), and reward processing (anticipation P3 (P3), feedback‐related negativity (FRN)) among never‐smoking adolescents. Methods Eighty‐four never‐smoking adolescents (nonexposed = 32, exposed = 52) performed a smoking cue reactivity, a Go/NoGo, and a monetary incentive delay (MID) task while ERPs were measured. Results Exposed and nonexposed groups did not differ in ERPs reflecting smoking cue reactivity, inhibitory control, and reward processing. A negative correlation between ETS exposure and the anticipatory P3 suggests reduced anticipatory reward sensitivity for nondrug rewards with increased levels of ETS exposure. However, since this effect was not consistent across analyses, no strong conclusions can be formulated. In the current study, few participants reported high levels of ETS exposure; therefore, further study is necessary. Conclusions Nevertheless, from this study, it can be concluded that low‐to‐moderate exposure to ETS during adolescence does not result in functional brain changes related to smoking cue reactivity, inhibitory control, and reward processing., This study tested the associations between ETS exposure and ERPs reflecting cue reactivity (P3, LPP), inhibitory control (N2, P3), and reward processing (anticipation P3 (P3), feedback‐related negativity (FRN)) among never‐smoking adolescents.
- Published
- 2020