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Start Over Descriptor "Lymphoid Progenitor Cells transplantation" Topic adoptive transfer

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1 results on '"Lymphoid Progenitor Cells transplantation"'

1. Determination of the Fate and Function of Innate Lymphoid Cells Following Adoptive Transfer of Innate Lymphoid Cell Precursors.

Author

O'Sullivan TE and Sun JC

Subjects
Adipose Tissue immunology, Animals, Biomarkers, Cell Survival, Flow Cytometry, Immunophenotyping, Leukocytes immunology, Leukocytes metabolism, Liver immunology, Lymphoid Progenitor Cells transplantation, Mice, Mice, Knockout, Adoptive Transfer, Immunity, Innate, Lymphocytes immunology, Lymphocytes metabolism, Lymphoid Progenitor Cells immunology, Lymphoid Progenitor Cells metabolism
Abstract

Innate lymphoid cells are a heterogeneous family of tissue-resident and circulating lymphocytes that play an important role in host immunity. Recent studies have profiled the developmental pathways of mature ILCs and have identified ILC progenitors in the bone marrow through the use of transcription factor reporter mice. Here we describe methodology to identify and isolate bone marrow CHILP and ILC2 progenitor (ILC2P) cells based on cell surface marker expression for adoptive transfer into lymphopenic mice to track the fate of developing ILCs.

Published
2018
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