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1. Adrenal gland plasticity in lactating rats and mice is sufficient to maintain basal hypersecretion of corticosterone.

2. Chronic psychosocial stress in male mice causes an up-regulation of scavenger receptor class B type 1 protein in the adrenal glands.

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3. Chronic psychosocial stress results in sensitization of the HPA axis to acute heterotypic stressors despite a reduction of adrenal in vitro ACTH responsiveness.

4. Adrenal gland plasticity in lactating rats and mice is sufficient to maintain basal hypersecretion of corticosterone.

5. Chronic psychosocial stress in male mice causes an up-regulation of scavenger receptor class B type 1 protein in the adrenal glands.