Search

Objectives: We undertook this study to examine the relationships between clinical symptoms as evaluated by Washington Neuropathic Pain Scale (NPS) and electrodiagnostic classification in patients with carpal tunnel syndrome (CTS). Methods: Eighty patients with unilateral CTS were included in this study. After diagnosis of CTS by electromyography, all patients completed a 10-item questionnaire (NPS). Results: A statistically significant correlation between total NPS score and severity of CTS was found (p=0.013, r=0.276). Conclusion: The present study indicates that using NPS might be useful in evaluating the clinical outcome of patients with CTS.

Scientific Background: The incidence of cerebrovascular diseases (CVD) among young adults is approximately 2-11/100.000. Etiological diagnosis is very heteregenous including cardioembolism as the most common cause. Patients and Methods: Twenty-five young patients (age between 18-45 years) with cerebrovascular disease who were admitted to our University Hospital in the last two years were evaluated for their etiological diagnoses and risk factors. They were classified according to the Trial of Org 10172 in acute stroke treatment (TOAST) classification. A comparison according to gender and age was done. Results: There were ten male (40%) and fifteen female (60%) patients. The mean age of the patients was 34.7 +/- 7.8 (20-45) years. The most frequent etiological diagnosis was cardioembolism related CVD (32%). Other etiological diagnoses were: Other determined causes 24% lacunar infarct 16%, large artery atherosclerosis 4% and undetermined 24%. The most common reason for cardioembolism was valvulopathy due to rheumatic fever (75%). Comparison of risk factors amongst genders and different age groups were not statistically significant (p>0.05). Conclusion: Despite complete evaluation, etiological diagnosis can not be determined in 24% of patients. Absence of classification for young adults and insufficiency at genetic research opportunities causes important limitations in clinical evaluation.

Objectives: We undertook this study to examine the relationships between clinical symptoms as evaluated by Washington Neuropathic Pain Scale (NPS) and electrodiagnostic classification in patients with carpal tunnel syndrome (CTS). Methods: Eighty patients with unilateral CTS were included in this study. After diagnosis of CTS by electromyography, all patients completed a 10-item questionnaire (NPS). Results: A statistically significant correlation between total NPS score and severity of CTS was found (p=0.013, r=0.276). Conclusion: The present study indicates that using NPS might be useful in evaluating the clinical outcome of patients with CTS.

The authors report here a case of sudden developed severe akathisia and parkinsonism with basal ganglia lesions in a 52-years-old diabetic uremic patient. Magnetic resonance of brain showed hyperintensities on T1 weighted images on bilateral basal ganglia.

Talamus ve beyin sapı inmeleri organik hipersomniye neden olabilirler. Paramedian talamusun uyku regülasyonunda önemli rol oynadığına inanılır ve uyku regülasyon bozukluklarının paramedian talamus inmelerinde (PTİ) ortaya çıkabileceği bilinmektedir. Tek taraflı ve sınırlı lezyonu olan PTİ'li hastalarda hafif uyku hali daha önceden bildirilmiştir. Bu yazıda manyetik rezonans görüntülemede (MRG) sınırlı, tek taraflı talamodiensefalik iskemik lezyonu olan ancak ciddi hipesomni ile kendini gösteren bir olgu sunulmaktadır. 54 yaşında, erkek hasta hastanemize gün içi aşırı uyku hali yakınması ile başvurdu. Çekilen kranial MRG'de solda talamus seviyesinden başlayarak nükleus Ruber ve Edinger Westpall nükleusuna uzanan iskemik lezyon saptandı. İlk hafta hastanın gün boyu toplam uyku saati 23-24 saat olarak seyretti. Hastaya dopamin agonisti tedavisi başlandı (bromokriptin 2.5mg/gün başlanarak 7.5mg/gün dozuna çıkıldı). Bu tedavi ile hastanın gün boyu uyku saati basamaklı olarak azaldı ve iki ay sonra hasta normal vijilansına geri döndü. Talamus ve mezensefalik veya pontin tegmental retiküler formasyonu etkileyen lezyonlar hipersomninin nedenlerinden biridir fakat klinik prezentasyon ve hipersomninin derecesi beynin etkilenen bölgesine bağlı olarak oldukça değişken olabilmektedir. Uyku ve uyanıklığın farklı beyin yapılarınca regülasyonunun hala anlaşılması zor olduğu ve yeni olgu bildirileri ve klinik çalışmaların bu durumun daha iyi anlaşılabilmesi için faydalı olacağı görüşündeyiz.

Thyrotoxic periodic paralysis (TPP) is an uncommen complication of hyperthyroidism. Patients present with acute onset of proximal symmetrical lower-extremity muscle weakness during the early morning hours or while resting after strenuous exertion and a high-carbohydrate meal. Almost all patients have hypokalemia. Thyrotoxic normokalemic periodic paralysis (TNPP) is actually very rare, only a few cases have been reported previously. In this paper we describe a case of TNPP in a 38 years old men, who developed acutely weakness in all extremities. The epidemiology, pathophysiology, clinical presentation, and therapy of thyrotoxic periodic paralysis were discussed in the light of the literature.