1. Prevalence of hypertriglyceridemia in adults and related cardiometabolic factors. SIMETAP-HTG study
- Author
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Antonio, Ruiz-García, Ezequiel, Arranz-Martínez, Beatriz, López-Uriarte, Montserrat, Rivera-Teijido, David, Palacios-Martínez, Gema M, Dávila-Blázquez, Antonio, Rosillo-González, José Antonio, González-Posada Delgado, José Enrique, Mariño-Suárez, Enrique, Revilla-Pascual, José Luis, Quintana-Gómez, Ignacio, Íscar-Valenzuela, Rafael, Alonso-Roca, Ana Pilar, Javierre-Miranda, Rosa Ana, Escrivá-Ferrairó, Isabel, Tello-Meco, Ana María, Ibarra-Sánchez, M Isabel, Gutiérrez Sánchez, Juan Ramón, Iglesias Quintana, M Inmaculada, Hernández-Beltrán, Montserrat, Pérez Fernández, Elena, Barrios-Rueda, Raúl, Pérez Muñoz, Miguel, Prieto Marcos, Santiago, Delgado Rodríguez, Raquel, Pleite Raposo, Rafael, Rodríguez-Cabanillas, M Rosario, Morales-Chico, Diana, Fernández-Pacheco Vila, Beatriz, Remón-Pérez, M Jesús, Del Villar Redondo, Joaquina, Reguillo-Díaz, Paloma, Aguilera Reija, Ana Olga, Rodríguez Rodríguez, Ofelia, Gómez-Fernández, M Del Carmen, Antón-Sanz, Antonio, Sánchez-Calso, Norma Alejandra, Doria-Carlin, and Manuel J, Frías-Vargas
- Subjects
Adult ,Hypertriglyceridemia ,Male ,Analysis of Variance ,Arteriosclerosis ,Hypercholesterolemia ,Fatty Liver ,Age Distribution ,Cross-Sectional Studies ,Metabolic Diseases ,Diabetes Mellitus ,Prevalence ,Humans ,Female ,Obesity ,Renal Insufficiency, Chronic ,Sex Distribution ,Triglycerides - Abstract
To determine in the adult population the crude and the sex- and age-adjusted prevalence rates of hypertriglyceridaemia (HTG) and to assess its association with cardiovascular risk factors, chronic kidney disease, cardiovascular and cardiometabolic diseases.Cross-sectional observational study conducted in Primary Care, with 6,588 adult study subjects, randomly selected on base-population. Patients had HTG if the triglyceride level was≥150mg/dL (≥1.7mmol/L), or were on lipid-lowering therapy to lower triglyceride. Associations were assessed by univariate and multivariate analysis, and crude and sex- and age-adjusted prevalence rates were determined.The arithmetic and geometric means of triglyceride levels were respectively 120.5 and 104.2mg/dL in global population, 135.7 and 116.0mg/dL in men, and 108.6 and 95.7mg/dL in women. The crude HTG prevalence rates were 29.6% in global population, 36.9% in men and 23.8% in women. The sex- and age-adjusted HTG prevalence rates were 27.0% in global population, 34.6% in men and 21.4% in women. The independent variables that were most associated with HTG were hypercholesterolemia (OR: 4.6), low HDL-C (OR: 4.1), hepatic steatosis (OR: 2.8), diabetes (OR: 2.0), and obesity (OR: 1.9).The means of triglyceride levels and HTG prevalence rates are intermediate between those of other national and international studies. A fifth of the female adult population and more than a third of the male population had HTG. The independent factors associated with HTG were hypercholesterolemia and low HDL-C, and the cardiometabolic variables diabetes, hepatic steatosis and obesity.
- Published
- 2020