1. Vertical transmission of hepatitis C: Testing and health-care engagement
- Author
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Sharon, Reid, Carolyn A, Day, David G, Bowen, Jeannie, Minnis, Joanne, Ludlow, Sue, Jacobs, Adrienne, Gordon, and Paul S, Haber
- Subjects
Adult ,Medical Audit ,Australia ,Hepacivirus ,Hepatitis C ,Infectious Disease Transmission, Vertical ,Cohort Studies ,Young Adult ,Pregnancy ,Risk Factors ,Child, Preschool ,Surveys and Questionnaires ,Humans ,Female - Abstract
To investigate hepatitis C virus (HCV) testing patterns and engagement with health care for women positive for HCV antibodies (anti-HCV) in pregnancy and their children through pregnancy and the first 2 years of the child's life.At a large inner-city Australian hospital from 2010 to 2012, anti-HCV positive pregnant women were recruited into a cohort study from pregnancy to 2 years post-delivery. Maternal and child data were collected by questionnaire and medical record extraction.During the study 29 women participants delivered 31 children. HCV RNA was detected in 64% (18/28) of pregnancies, with injecting drug use, the most likely route of maternal infection. Relatively high maternal health-care engagement during pregnancy reduced after delivery. There was evidence of ongoing illicit drug use in the majority of women. Of the children, 58% (18/31) had some HCV testing confirmed but complete testing was confirmed for only 10% (3/31). Largely, testing was incomplete or unknown. No vertical transmission was identified. Forty-two percent (13/31) of children were placed in out-of-home-care.Potentially, there is a high risk of inadequate or incomplete HCV testing of vulnerable children. Ongoing maternal drug use, poor maternal health-care engagement and placement in out-of-home-care may increase the risk. Complete testing of all children at risk of vertically acquired HCV needs to be ensured.
- Published
- 2017