1. Associations between pretreatment physical performance tests and treatment complications in patients with non-small cell lung cancer: A systematic review
- Author
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M.J.J. Voorn, R.F.W. Franssen, J.M.W.F. Verlinden, Bart C. Bongers, Maryska L.G. Janssen-Heijnen, G. Bootsma, and Dirk Karel Maria De Ruysscher
- Subjects
WALK TEST ,0301 basic medicine ,Adult ,medicine.medical_specialty ,RESECTION ,Lung Neoplasms ,Preoperative risk assessment ,SURGERY ,Prehabilitation ,Physical exercise ,OBSTRUCTIVE PULMONARY-DISEASE ,EXERCISE CAPACITY ,6-MIN WALK ,03 medical and health sciences ,0302 clinical medicine ,Treatment complications ,Postoperative Complications ,Aerobic capacity ,Internal medicine ,Carcinoma, Non-Small-Cell Lung ,medicine ,Humans ,In patient ,Stage (cooking) ,INCREASED RISK ,Lung cancer ,business.industry ,Hematology ,Physical Functional Performance ,medicine.disease ,HOSPITAL STAY ,Test (assessment) ,OXYGEN-CONSUMPTION ,030104 developmental biology ,Oncology ,030220 oncology & carcinogenesis ,Exercise Test ,Non small cell ,business ,Perioperative care - Abstract
This systematic review evaluated which outcome variables and cut-off values of pretreatment exercise tests are associated with treatment complications in patients with stage I-III non-small cell lung cancer (NSCLC). PRISMA and Cochrane guidelines were followed. A total of 38 studies with adult patients undergoing treatment for stage I-III NSCLC who completed pretreatment exercise tests, and of whom treatment-related complications were recorded were included. A lower oxygen uptake at peak exercise amongst several other variables on the cardiopulmonary exercise test and a lower performance on field tests, such as the incremental shuttle walk test, stair-climb test, and 6-minute walk test, were associated with a higher risk for postoperative complications and/ or postoperative mortality. Cut-off values were reported in a limited number of studies and were inconsistent. Due to the variety in outcomes, further research is needed to evaluate which outcomes and cut-off values of physical exercise tests are most clinically relevant.
- Published
- 2020