1. Primary immune deficiencies presenting in adults: seven years of experience from Iran
- Author
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Nahal Mansouri, Davood Mansouri, Jean L. Casanova, Payam Tabarsi, Mohammad R. Masjedi, M. Amiri, Ali Cheraghvandi, R. Kevin Elwood, Ali Akbar Velayati, David P. Speert, Masoud Motavasseli, Noushin Baghaii, Parisa Adimi, Reza Rouhi, Hamid R. Jamaati, R. Robert Schellenberg, Soheila Zahirifard, Stuart E. Turvey, Mehdi Mirsaedi, Forouzan Mohammadi, and Navid Ahmady Roozbahany
- Subjects
Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Neutropenia ,Adolescent ,Immunology ,Leukocyte-Adhesion Deficiency Syndrome ,MEDLINE ,Immunoglobulins ,Complement C1 Inactivator Proteins ,Iran ,Timely diagnosis ,Diagnosis, Differential ,Ataxia Telangiectasia ,Agammaglobulinemia ,Immunology and Allergy ,Medicine ,Humans ,Serpins ,Aged ,Retrospective Studies ,Immunity, Cellular ,Adult patients ,business.industry ,Retrospective cohort study ,Genetic Diseases, X-Linked ,Middle Aged ,medicine.disease ,Optimal management ,Wiskott-Aldrich Syndrome ,Common Variable Immunodeficiency ,Warning signs ,Primary immunodeficiency ,Female ,business ,Complement C1 Inhibitor Protein ,Job Syndrome - Abstract
Primary immunodeficiencies (PIDs) are not solely diseases of childhood. We describe the clinical presentation and outcome for 55 adult patients with previously unrecognized PIDs. This series provides unique data regarding PIDs presenting in adulthood, and serves as a timely reminder that physicians must consider the diagnosis of PIDs in their adult patients. Using the experience gained from these patients, we outline key “warning signs” suggestive of an underlying PID. Only through increased physician awareness will patients with PIDs receive timely diagnosis and optimal management.
- Published
- 2005