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Your search keyword '"A. D. van der Zwan"' showing total 2 results
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2 results on '"A. D. van der Zwan"'

1. Trigger-happy resident memory CD4

Author

A E, Oja, B, Piet, C, Helbig, R, Stark, D, van der Zwan, H, Blaauwgeers, E B M, Remmerswaal, D, Amsen, R E, Jonkers, P D, Moerland, M A, Nolte, R A W, van Lier, and P, Hombrink

Subjects
CD4-Positive T-Lymphocytes, Cytotoxicity, Immunologic, Male, Mice, Knockout, Receptors, Notch, Middle Aged, Mice, Inbred C57BL, Interferon-gamma, Mice, Gene Expression Regulation, Antigens, CD, Immunoglobulin J Recombination Signal Sequence-Binding Protein, Animals, Humans, Female, T-Box Domain Proteins, Transcriptome, Immunologic Memory, Integrin alpha Chains, Lung, Aged
Abstract

Resident memory T cells (T

Published
2017

2. Rating impairment and disability in Parkinson's disease: Evaluation of the unified Parkinson's disease rating scale

Author

A. D. van der Zwan, J.J. van Hilten, Aeilko H. Zwinderman, and R. A. C. Roos

Subjects
Adult, Male, medicine.medical_specialty, Parkinson's disease, Activities of daily living, Unified Parkinson's disease rating scale, Disease, behavioral disciplines and activities, Antiparkinson Agents, Disability Evaluation, Rating scale, Activities of Daily Living, medicine, Humans, Set (psychology), Reliability (statistics), Aged, Aged, 80 and over, Neurologic Examination, Disease progression, Reproducibility of Results, Parkinson Disease, Middle Aged, medicine.disease, Neurology, Physical therapy, Female, Neurology (clinical), Psychology
Abstract

Although the Unified Parkinson's Disease Rating Scale (UPDRS) is widely used to monitor disease progression and drug efficacy, no attempts have been made to evaluate its scientific and clinical quality. Poor clinical sensibility of items in the activities of daily living (ADL) section and redundancy of items in the motor examination (ME) section prompted us to determine if the number of items in these sections could be reduced to a smaller, equally sensitive set that would describe the data as reliably as did the original set of items. Therefore, we assessed 111 patients with idiopathic Parkinson's disease on the UPDRS and Hoehn and Yahr staging scales. Our results show that the ADL (13 items) and ME (14 items) sections can be reduced to 8 items each without loss of reliability or validity. Our report is preliminary and needs validation.

Published
1994
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