1. The effects of age on dyspnea and respiratory mechanical and neural responses to exercise in healthy men
- Author
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William MacAskill, Ben Hoffman, Michael A. Johnson, Graham R. Sharpe, Joshua Rands, Shoena E. Wotherspoon, Yaroslav Gevorkov, Tracy L. Kolbe‐Alexander, and Dean E. Mills
- Subjects
aging ,dyspnea ,exercise ,mechanical ,neural ,Physiology ,QP1-981 - Abstract
Abstract The respiratory muscle pressure generation and inspiratory and expiratory neuromuscular recruitment patterns in younger and older men were compared during exercise, alongside descriptors of dyspnea. Healthy younger (n = 8, 28 ± 5 years) and older (n = 8, 68 ± 4 years) men completed a maximal incremental cycling test. Esophageal, gastric (Pga) and transdiaphragmatic pressures, and electromyography (EMG) of the crural diaphragm were measured using a micro‐transducer and EMG catheter. EMG of the parasternal intercostals, sternocleidomastoids, and rectus abdominis were measured using skin surface electrodes. After the exercise test, participants completed a questionnaire to evaluate descriptors of dyspnea. Pga at end‐expiration, Pga expiratory tidal swings, and the gastric pressure–time product (PTPga) at absolute and relative minute ventilation were higher (p
- Published
- 2023
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