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Submitted by Cristiane Chim (cristiane.chim@ucpel.edu.br) on 2016-12-20T19:00:41Z No. of bitstreams: 1 Sandra Lhullier (1).pdf: 820845 bytes, checksum: 4360a70cd874fcf17c790f46b97efa14 (MD5) Made available in DSpace on 2016-12-20T19:00:41Z (GMT). No. of bitstreams: 1 Sandra Lhullier (1).pdf: 820845 bytes, checksum: 4360a70cd874fcf17c790f46b97efa14 (MD5) Previous issue date: 2015-10-01 Objective: Evaluate non adherence to antiretroviral therapy and its associated factors in patients living with HIV / AIDS (PLWHA) treated at a referral Center in Southern Brazil. Methods: The ecological study of retrospective survey was developed in the Specialized Care Service (SAE) in the city of Pelotas. Adherence was assessed using the antiretroviral dispensing record (ARV) for the dispenser unit of drugs (UDM). The sample consisted of patients who withdrew their ARV in the first fifteen days of June 2013 and were followed for one year. The associated factors were evaluated by retrospective data collection from medical records. The mean time between removals was calculated to categorize patients into proper adherence and non-adherence. Patients who had taken ARV higher than the average of 37 days between withdrawals and / or abandoned the withdrawal of ARV were considered non-adherent. Results: 473 patients were eligible for the study. The prevalence of non-adherence was 25.6 %.The variables significantly associated with non-adherence were age < 45 years (p = 0.001), detectable viral load (p < 0.001), absence of clinical comorbidity of ischemic heart disease (p < 0.001). They have tended to increase risk of nonadherence: not present dyslipidemia (p=0. 07) and be in current or initial use scheme with IP (95% IC 0,99 to 1,14). Conclusions: Younger and seemingly healthier patients have higher proportions of non-adherence. Strategies to promote better adherence in this population should be prioritized by PLWHA services. Objetivo: Avaliar à não adesão à terapia antirretroviral e seus fatores associados, em pacientes vivendo com HIV/AIDS (PVHA) atendidos em um centro de referência no sul do Brasil. Métodos: O estudo ecológico de levantamento retrospectivo foi desenvolvido no Serviço de Assistência Especializada (SAE) na cidade de Pelotas-RS. A adesão foi avaliada através do registro de dispensação de antirretrovirais (ARV) pela unidade de dispensadora de medicamentos (UDM). A amostra foi de pacientes que retiraram seus ARV nos primeiros quinze dias de junho de 2013 e acompanhados por um ano. Os fatores associados foram avaliados por coleta de dados retrospectivos de prontuários médicos. Foi calculada a média de tempo entre as retiradas para categorizar os pacientes em adesão adequada e não adesão. Pacientes que apresentaram retiradas de ARV superior à média de 37 dias entre as retiradas e /ou abandonaram a retirada de ARV foram considerados não aderentes. Resultados: Foram elegíveis para o estudo 473 pacientes. A prevalência de não adesão foi de 25,6%. As variáveis significativamente associadas a não adesão foram: idade < 45 anos (p=0,001), carga viral detectável (p