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Start Over Author "Lessells, Richard" Topic aids patients Topic covid-19
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1. Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection With accumulation of mutations in a patient with poorly controlled Human Immunodeficiency Virus infection.

Author

Maponga, Tongai G, Jeffries, Montenique, Tegally, Houriiyah, Sutherland, Andrew, Wilkinson, Eduan, Lessells, Richard J, Msomi, Nokukhanya, Zyl, Gert van, Oliveira, Tulio de, and Preiser, Wolfgang

Subjects
HIV infections, COVID-19, GENETIC mutation, IMMUNOCOMPROMISED patients, CHRONIC diseases, WOMEN, HIGHLY active antiretroviral therapy, INFECTION, RESEARCH funding, AIDS patients
Abstract

A 22-year-old woman with uncontrolled advanced human immunodeficiency virus (HIV) infection was persistently infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) beta variant for 9 months, the virus accumulating >20 additional mutations. Antiretroviral therapy suppressed HIV and cleared SARS-CoV-2 within 6 to 9 weeks. Increased vigilance is warranted to benefit affected individuals and prevent the emergence of novel SARS-CoV-2 variants. [ABSTRACT FROM AUTHOR]

Published
2023
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