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Start Over Author "Guo CP" Topic aids-related opportunistic infections
2 results on '"Guo CP"'

1. A Retrospective Study of Culture-confirmed Mycobacterial Infection among Hospitalized HIV-infected Patients in Beijing, China.

Author

Zhao XY, Zeng ZY, Hua WH, Yu YH, Guo CP, Zhao XQ, Dong HY, Liu J, and Wan KL

Subjects
AIDS-Related Opportunistic Infections epidemiology, Adult, Beijing, Coinfection, Extensively Drug-Resistant Tuberculosis epidemiology, Extensively Drug-Resistant Tuberculosis microbiology, Female, HIV Infections epidemiology, Hospitals, Urban, Humans, Male, Mycobacterium Infections, Nontuberculous epidemiology, Mycobacterium tuberculosis isolation & purification, Nontuberculous Mycobacteria isolation & purification, Prevalence, Retrospective Studies, Sputum microbiology, Tuberculosis, Multidrug-Resistant epidemiology, Tuberculosis, Pulmonary epidemiology, AIDS-Related Opportunistic Infections microbiology, HIV Infections microbiology, Mycobacterium Infections, Nontuberculous microbiology, Tuberculosis, Multidrug-Resistant microbiology, Tuberculosis, Pulmonary microbiology
Abstract

A retrospective analysis was performed in two major HIV/AIDS referral hospitals in Beijing to evaluate the prevalence of Mycobacterium tuberculosis (MTB) and non-tuberculous mycobacterial (NTM) infections in HIV-infected patients. A total of 627 patients' data were reviewed, and 102 (16.3%) patients were diagnosed with culture-confirmed mycobacterial infection, including 84 with MTB, 16 with NTM, and 2 with both MTB and NTM. The most frequent clinical complication by mycobacterial infection was pulmonary infection (48/102, 47.1%). The overall rates of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB) were 11.9% and 3.4%, respectively. This study underlines the urgent need to intensify screening for mycobacteria coinfection with HIV and to prevent the spread of drug-resistant TB among HIV-infected patients., (Copyright © 2018 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.)

Published
2018
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2. Molecular Characteristics and Drug Susceptibility of Mycobacterium tuberculosis Isolates from Patients Co-infected with Human Immunodeficiency Virus in Beijing, China.

Author

Liu J, Wang HZ, Lian LL, Yu YH, Zhao XQ, Guo CP, Liu HC, Liu SM, Zhao H, Zeng ZY, Zhao XY, and Wan KL

Subjects
China, Humans, Microbial Sensitivity Tests, Mycobacterium tuberculosis classification, Mycobacterium tuberculosis isolation & purification, Phylogeny, Tuberculosis microbiology, AIDS-Related Opportunistic Infections microbiology, Antitubercular Agents pharmacology, Mycobacterium tuberculosis drug effects, Tuberculosis complications
Abstract

70 clinical Mycobacterium tuberculosis strains isolated from AIDS patients in two HIV/AIDS referral hospitals in Beijing were used in this study. M. tuberculosis and non-tuberculosis mycobacterium (NTM) were identified by using multi-locus PCR. M. tuberculosis was genotyped by using 15-locus MIRU-VNTR technique and spoligotyping afterwards. Meanwhile, the drug susceptibilities of the strains to the four first-line anti TB drugs (rifampin, isoniazid, streptomycin, and ethambutol) and the four second-line anti-TB drugs (capreomycin, kanamycin, ofloxacin, and ethionanide) were tested with proportional method. In this study, M. tuberculosis and NTM strains isolated from AIDS patients with TB-like symptoms were identified and genotyping analysis indicated that Beijing genotype was the predominant genotype. In addition, the prevalence of drug-resistant TB, especially the prevalence of XDR-TB, was higher than that in TB patients without HIV infection., (Copyright © 2015 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.)

Published
2015
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