1. [Alpha-glucosidase and alanine-amino-peptidase in the early diagnosis of renal failure in obstructive jaundice].
- Author
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Lazzara S, Pergolizzi FP, Melita G, Cavaleri A, Tigano D, and Riso F
- Subjects
- Adult, Aged, Cholestasis enzymology, Diagnosis, Differential, Female, Humans, Kidney Failure, Chronic enzymology, Kidney Failure, Chronic etiology, Male, Middle Aged, Time Factors, Alanine metabolism, Aminopeptidases blood, Cholestasis complications, Kidney Failure, Chronic diagnosis, alpha-Glucosidases blood
- Abstract
Renal failure is a serious complication of obstructive jaundice. Early diagnosis and prevention of spontaneous evolution of the disease can improve prognosis, otherwise very poor in many cases. The Authors, on the basis of experimental researches from literature, expose their clinical experience about the validity of the determination of Alpha-Glucosidase and Alanine-Amino-Peptidase for early diagnosis and differentiation between organic or functional forms of renal failure. They conclude that determination of urinary levels of AGS and AAP is a valid aid for the evaluation of renal function in patients with obstructive jaundice.
- Published
- 1997