1. Synthesis and crystal structure of peptide dimethyl biphenyl hybrid C52H60N6O100.25H2O.
- Author
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Xuan Tu Nguyen, Thuy Quynh Le, Tra My Bui Thi, Dinh Hung Mac, and Thai Thanh Thu Bui
- Subjects
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CRYSTAL structure , *PROLINE , *ALANINE , *METHYL groups , *HYDROGEN bonding , *X-ray diffraction , *BIPHENYL compounds , *AMINES - Abstract
The synthesis and crystal structure of peptide 6,60-dimethyl biphenyl hybrid are described. The title compound was synthesized by reaction between 6,60- dimethyl-[1,1'-biphenyl]-2,2'-dicarbonyl dichloride in CH2Cl2, amine HN-- proline--phenylalanine--alanine--COOMe and Et3N at 273 K under N2 atmosphere and characterized by single-crystal X-ray diffraction. The asymmetric unit contains one peptide molecule and a quarter of a water molecule. A disorder of a methyl and methoxycarbonyl group of one alanine residue is observed with occupancy ratio 0.502 (6):0.498 (6). The structure is consolidated by intra- and intermolecular hydrogen bonds. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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