1. Carbohydrate-deficient transferrin, a sensitive biomarker and diagnostic parameter in non-alcoholic fatty liver
- Author
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Gabriella Lengyel, György Szabó, Emil Fraenkel, Peter Jarčuška, Elek Dinya, Ivica Lazúrová, and János Fehér
- Subjects
medicine.medical_specialty ,Cirrhosis ,medicine.diagnostic_test ,Triglyceride ,business.industry ,Fatty liver ,Carbohydrate deficient transferrin ,medicine.disease ,Gastroenterology ,Liver disease ,chemistry.chemical_compound ,Endocrinology ,chemistry ,Internal medicine ,medicine ,General Earth and Planetary Sciences ,Alcoholic fatty liver ,Liver function tests ,business ,Body mass index ,General Environmental Science - Abstract
The non-alcoholic fatty liver (NAFLD) is an aquired metabolic liver disease as a consequence of triglyceride accummulation within the liver cells. It is accompanied by necrobiotic inflammatory reaction, fibrosis and also by liver cirrhosis. Its differentiation from alcoholic fatty liver (AFLD) looks sometimes to be difficult. It is simple knowing the clear anamnesis, but if the individual does not want to inform us about the alcohol consumption, the differentiation is not very easy. Aim of the study: The aim was to determine the value of carbohydrate deficient transferrin (CDT) in patients with non-alcoholic fatty liver, as well as to analyse the high values according to the anamnesis. Patients and methods: The group of patients consisted of 39 individuals, whose ultrasound examination showed the signs characteristic of fatty liver. The sex rate was: 21 female and 18 male patients. The values of CDT, body mass index (BMI) and HOMA index were determined. The mean value of CDT was: 239±0,52% (in ma...
- Published
- 2009
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