1. 3D T2-weighted spin echo imaging in the breast.
- Author
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Moran CJ, Hargreaves BA, Saranathan M, Lipson JA, Kao J, Ikeda DM, and Daniel BL
- Subjects
- Female, Humans, Image Enhancement methods, Observer Variation, Pilot Projects, Reproducibility of Results, Sensitivity and Specificity, Spin Labels, Algorithms, Breast Neoplasms pathology, Diffusion Magnetic Resonance Imaging methods, Echo-Planar Imaging methods, Image Interpretation, Computer-Assisted methods, Imaging, Three-Dimensional methods
- Abstract
Purpose: To evaluate the performance of 2D versus 3D T2-weighted spin echo imaging in the breast., Materials and Methods: 2D and 3D T2-weighted images were acquired in 25 patients as part of a clinically indicated breast magnetic resonance imaging (MRI) exam. Lesion-to-fibroglandular tissue signal ratio was measured in 16 identified lesions. Clarity of lesion morphology was assessed through a blinded review by three radiologists. Instances demonstrating the potential diagnostic contribution of 3D versus 2D T2-weighted imaging in the breast were noted through unblinded review by a fourth radiologist., Results: The lesion-to-fibroglandular tissue signal ratio was well correlated between 2D and 3D T2-weighted images (R(2) = 0.93). Clarity of lesion morphology was significantly better with 3D T2-weighted imaging for all observers based on a McNemar test (P ≤ 0.02, P ≤ 0.01, P ≤ 0.03). Instances indicating the potential diagnostic contribution of 3D T2-weighted imaging included improved depiction of signal intensity and improved alignment between DCE and T2-weighted findings., Conclusion: In this pilot study, 3D T2-weighted imaging provided comparable contrast and improved depiction of lesion morphology in the breast in comparison to 2D T2-weighted imaging. Based on these results further investigation to determine the diagnostic impact of 3D T2-weighted imaging in breast MRI is warranted., (Copyright © 2013 Wiley Periodicals, Inc.)
- Published
- 2014
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