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Your search keyword '"Qiao, Hong"' showing total 2 results
2 results on '"Qiao, Hong"'

1. Construction of AE ring system for the C19-diterpenoid alkaloids with a 5β-hydroxyl group

Author

Yang, Zhan-Kun, Chen, Qiao-Hong, and Wang, Feng-Peng

Subjects
*DITERPENES, *HYDROXYL group, *CYCLIC compounds, *MANNICH reaction, *ASYMMETRIC synthesis, *NUCLEOPHILIC reactions, *ALKALOIDS
Abstract

Abstract: An AE azabicyclic fragment, with a β-hydroxyl group at C-5 and a substituent at C-1, of the C19-diterpenoid alkaloids, was synthesized. The key reactions include an intramolecular Claisen-type condensation, double Mannich reaction, and stereoselective nucleophilic addition of carbonyl group with the assistance of steric effect of 1β-substituent. [Copyright &y& Elsevier]

Published
2011
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2. Construction of A/E/F ring systems of C19-diterpenoid alkaloids with both C-1 and C-6 oxygen functions

Author

Liu, Zhi-Gang, Xu, Liang, Chen, Qiao-Hong, and Wang, Feng-Peng

Subjects
*ALKALOIDS, *DITERPENES, *OXYGEN, *CYCLIC compounds, *DIELS-Alder reaction, *MANNICH reaction, *METHYL groups, *ASYMMETRIC synthesis, *FUNCTIONAL groups
Abstract

Abstract: An tricyclic AEF fragment of C19-diterpenoid alkaloid bearing an angular methyl group and the oxygen function groups at C-1 and C-6 was successfully synthesized. The synthesis features a stereoselective intramolecular Diels–Alder reaction and a highly efficient intramolecular Mannich reaction as well as efficient functional groups transformations. [Copyright &y& Elsevier]

Published
2012
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