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Your search keyword '"Miao, Yufeng"' showing total 2 results
Start Over Author "Miao, Yufeng" Topic alkenes
2 results on '"Miao, Yufeng"'

1. Biocatalytic Michael-type additions of acetaldehyde to nitroolefins with the proline-based enzyme 4-oxalocrotonate tautomerase yielding enantioenriched γ-nitroaldehydes.

Author

Geertsema EM, Miao Y, Tepper PG, de Haan P, Zandvoort E, and Poelarends GJ

Subjects
Acetaldehyde chemistry, Alkenes chemistry, Biocatalysis, Carbon chemistry, Stereoisomerism, gamma-Aminobutyric Acid metabolism, Acetaldehyde metabolism, Alkenes metabolism, Isomerases metabolism, Nitro Compounds chemistry, Proline chemistry
Abstract

Call me Michaelase: The enzyme 4-oxalocrotonate tautomerase (4-OT) promiscuously catalyzes the Michael-type addition of acetaldehyde to a collection of aromatic and aliphatic nitroolefins with high stereoselectivity producing precursors of γ-aminobutyric acid (GABA) analogues., (Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2013
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2. Biocatalytic Michael-Type Additions of Acetaldehyde to Nitroolefins with the Proline-Based Enzyme 4-Oxalocrotonate Tautomerase Yielding Enantioenriched γ-Nitroaldehydes.

Author

Geertsema, Edzard M., Miao, Yufeng, Tepper, Pieter G., de Haan, Pim, Zandvoort, Ellen, and Poelarends, Gerrit J.

Subjects
NITROALKENES, ENZYMES, ALKENES, NITRO compounds, ALIPHATIC compounds, ALDEHYDES
Abstract

Call me Michaelase: The enzyme 4‐oxalocrotonate tautomerase (4‐OT) promiscuously catalyzes the Michael‐type addition of acetaldehyde to a collection of aromatic and aliphatic nitroolefins with high stereoselectivity producing precursors of γ‐aminobutyric acid (GABA) analogues (see scheme). [ABSTRACT FROM AUTHOR]

Published
2013
Full Text
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